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NCT03057600 · ClinicalTrials.gov registry record · Phase 2

Study of CB-839 in Combination w/ Paclitaxel in Participants of African Ancestry and Non-African Ancestry With Advanced Triple Negative Breast Cancer (TNBC)

A Phase 2 study, sponsored by Calithera Biosciences.

Completed
Registry status
Phase 2
Development phase
52
Enrollment target

NCT03057600 is a Phase 2 study that has completed, run by Calithera Biosciences. The registered enrollment target is 52 participants.

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The verdict

NCT03057600, a Phase 2 study, has completed, sponsored by Calithera Biosciences.

COMPLETED
Registry status
Phase 2
Development phase
52 participants
Enrollment target

Study Summary

CX-839-007 is an open-label Phase 2 study of the combination of CB-839 with paclitaxel in participants of African ancestry and non-African ancestry with advanced triple negative breast cancer. Multiple single-arm cohorts will be enrolled in which 800 mg twice daily (BID) CB-839 will be administered in combination with the full approved dose of paclitaxel.

Interventions

  • DRUG Paclitaxel
  • DRUG CB-839

Trial Details

FieldValue
Enrollment Target 52 participants
Start Date 2017-05-01
Est. Completion 2019-11-25
Phase Phase 2

Sponsor

Calithera Biosciences

22 total trials

What the Registry Record Tells You About NCT03057600

The ClinicalTrials.gov registry entry for NCT03057600 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 52 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Calithera Biosciences, which has 22 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Paclitaxel is the first listed.

NCT03057600 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03057600 about?

NCT03057600 is a clinical study titled "Study of CB-839 in Combination w/ Paclitaxel in Participants of African Ancestry and Non-African Ancestry With Advanced Triple Negative Breast Cancer (TNBC)". CX-839-007 is an open-label Phase 2 study of the combination of CB-839 with paclitaxel in participants of African ancestry and non-African ancestry with advanced triple negative breast cancer. Multiple single-arm cohorts will be enrolled in which 800 mg twice daily (BID) CB-839 will be administered ...

What is the current status of trial NCT03057600?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 52 participants. The study started on 2017-05-01. Estimated completion is 2019-11-25.

What interventions are being tested in trial NCT03057600?

The interventions under investigation include: Paclitaxel (DRUG), CB-839 (DRUG).

Who is sponsoring clinical trial NCT03057600?

This trial is sponsored by Calithera Biosciences, which has 22 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.