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NCT03048721 · ClinicalTrials.gov registry record · NA
Skin Tape Harvesting for Transcriptomics Analysis
A NA study, sponsored by University of Michigan.
- Completed
- Registry status
- NA
- Development phase
- 15
- Enrollment target
NCT03048721: Completed NA study, sponsored by University of Michigan.
NCT03048721 is a NA study that has completed, run by University of Michigan. The registered enrollment target is 15 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03048721, a NA study, has completed, sponsored by University of Michigan.
- COMPLETED
- Registry status
- NA
- Development phase
- 15 participants
- Enrollment target
Study Summary
Transcriptomics is the study of how RNA is expressed under specific conditions. Transcriptomic analyses of lesional skin biopsies can be a useful way to track how a patient responds to a drug and separate out drug responders from non-responders. However, biopsies are painful, carry risk of bleeding infections and scarring. A non-invasive approach, such as tape-harvesting, to obtain transcriptomic data from psoriatic skin would increase our capabilities to monitor patients on treatment and potentially help us predict if the drug will be effective sooner. However, it is not known how well tape-harvesting can capture transcriptomic changes that are occurring in psoriatic skin. The purpose of this study is to address how well tape-harvesting captures the transcriptomic changes that are occurring in psoriatic skin.
Primary Outcome
Fold Change of Human Beta Defensin2 (hBD2)
Interventions
- PROCEDURE Punch Biopsy
- PROCEDURE Skin Tape Stripping
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2017-08-14 |
| Est. Completion | 2018-09-24 |
| Phase | NA |
What the finished NCT03048721 record still lists
NCT03048721 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which Punch Biopsy is the first listed.
NCT03048721 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03048721 about?
NCT03048721 is a clinical study titled "Skin Tape Harvesting for Transcriptomics Analysis". Transcriptomics is the study of how RNA is expressed under specific conditions. Transcriptomic analyses of lesional skin biopsies can be a useful way to track how a patient responds to a drug and separate out drug responders from non-responders. However, biopsies are painful, carry risk of bleeding ...
What is the current status of trial NCT03048721?
This trial is currently completed. It is a NA study. The enrollment target is 15 participants. The study started on 2017-08-14. Estimated completion is 2018-09-24.
What interventions are being tested in trial NCT03048721?
The interventions under investigation include: Punch Biopsy (PROCEDURE), Skin Tape Stripping (PROCEDURE).
Who is sponsoring clinical trial NCT03048721?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03048721's enrollment target sits among peer trials
15 1881st of 2000 higher than 92 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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