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NCT03042923 · ClinicalTrials.gov registry record
Intestinal Permeability and Endometriosis
A clinical trial, sponsored by University of Tennessee.
- Completed
- Registry status
- 46
- Enrollment target
NCT03042923: Completed study, sponsored by University of Tennessee.
NCT03042923 is a clinical trial that has completed, run by University of Tennessee. The registered enrollment target is 46 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03042923 has completed, sponsored by University of Tennessee.
- COMPLETED
- Registry status
- 46 participants
- Enrollment target
Study Summary
The objective of this project will be to determine whether patients with a surgical diagnosis of endometriosis have impaired intestinal permeability as compared with healthy controls. This would suggest the presence of an environmentally triggered and intestinally mediated association in the etiology of endometriosis. This would be a proof of concept trial to establish whether there is in fact a relationship worthy of future research.
Primary Outcome
Urine is collected over six hours and is then measured for ratio of L:M. An L:M ratio \>0.10 is consistent with increased intestinal permeability. Normally the gut does not absorb lactulose unless permeability is present.
Interventions
- DRUG lactulose:mannitol (L:M) oral challenge
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 46 participants |
| Start Date | 2016-04 |
| Est. Completion | 2019-06 |
What the finished NCT03042923 record still lists
NCT03042923 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 46 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which lactulose:mannitol (L:M) oral challenge is the first listed.
NCT03042923 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03042923 about?
NCT03042923 is a clinical study titled "Intestinal Permeability and Endometriosis". The objective of this project will be to determine whether patients with a surgical diagnosis of endometriosis have impaired intestinal permeability as compared with healthy controls. This would suggest the presence of an environmentally triggered and intestinally mediated association in the etiolog...
What is the current status of trial NCT03042923?
This trial is currently completed. The enrollment target is 46 participants. The study started on 2016-04. Estimated completion is 2019-06.
What interventions are being tested in trial NCT03042923?
The interventions under investigation include: lactulose:mannitol (L:M) oral challenge (DRUG).
Who is sponsoring clinical trial NCT03042923?
This trial is sponsored by University of Tennessee, which has 96 total clinical trials registered on ClinicalTrials.gov.
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