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NCT03038932 · ClinicalTrials.gov registry record

Etiology of Eczema Herpeticum (EH)

A clinical trial, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
69
Enrollment target

NCT03038932: Completed study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

NCT03038932 is a clinical trial that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 69 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03038932 has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
69 participants
Enrollment target

Study Summary

Atopic dermatitis, also called eczema, is a disease with dry, scaly, itchy skin. Those with atopic dermatitis may have complications from skin infections such as eczema herpeticum after herpes simplex virus (HSV) infection. Symptoms of eczema herpeticum include fever and clusters of itchy blisters which crust over and form sores. Although exposure to HSV is widespread, most people clear the virus and only a subset of individuals with atopic dermatitis develop eczema herpeticum. The purpose of this study is to determine why some individuals with atopic dermatitis are at higher risk for recurrent skin infections with HSV. The study team will compare how people with atopic dermatitis with a history of recurrent eczema herpeticum, people with atopic dermatitis without a history of eczema herpeticum, and people without atopic dermatitis respond to HSV.

Primary Outcome

Whole genome sequencing methodology will be used to identify differences in frequency of rare deleterious coding genetic variants between recurrent Atopic Dermatitis (AD) subjects with a history of Eczema Herpeticum (ADEH+) and ≥3 Eczema Herpeticum (EH) episodes, versus controls. Controls will include (1) AD subjects without a history of EH (ADEH-); (2) non-atopic (NA) subjects without AD; and (3) general population controls from the Thousand Genomes Project.

Trial Details

FieldValue
Enrollment Target 69 participants
Start Date 2017-02-22
Est. Completion 2020-11-24

What the finished NCT03038932 record still lists

NCT03038932 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 69 participants, a relatively small participant target.

The record links to 0 conditions, and to 0 interventions.

NCT03038932 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03038932 about?

NCT03038932 is a clinical study titled "Etiology of Eczema Herpeticum (EH)". Atopic dermatitis, also called eczema, is a disease with dry, scaly, itchy skin. Those with atopic dermatitis may have complications from skin infections such as eczema herpeticum after herpes simplex virus (HSV) infection. Symptoms of eczema herpeticum include fever and clusters of itchy blisters w...

What is the current status of trial NCT03038932?

This trial is currently completed. The enrollment target is 69 participants. The study started on 2017-02-22. Estimated completion is 2020-11-24.

Who is sponsoring clinical trial NCT03038932?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

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Source: ClinicalTrials.gov NCT03038932, the US trial registry maintained by the National Library of Medicine. NCT03038932 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.