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NCT03031782 · ClinicalTrials.gov registry record · Phase 3

Secukinumab Safety and Efficacy in Juvenile Psoriatic Arthritis (JPsA) and Enthesitis-related Arthritis (ERA)

A Phase 3 study, sponsored by Novartis Pharmaceuticals.

Completed
Registry status
Phase 3
Development phase
86
Enrollment target

NCT03031782: Completed Phase 3 study, sponsored by Novartis Pharmaceuticals.

NCT03031782 is a Phase 3 study that has completed, run by Novartis Pharmaceuticals. The registered enrollment target is 86 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (89% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03031782, a Phase 3 study, has completed, sponsored by Novartis Pharmaceuticals.

COMPLETED
Registry status
Phase 3
Development phase
86 participants
Enrollment target

Study Summary

This was a double-blind, placebo-controlled, event-driven randomized withdrawal study to investigate the efficacy and safety of secukinumab treatment in the Juvenile Idiopathic Arthritis (JIA) categories of Juvenile Psoriatic Arthritis (JPsA) and Enthesitis-related Arthritis (ERA). The study was divided into 3 parts (plus a post-treatment follow-up period) consisting of open-label, single-arm active treatment in Treatment Periods 1 and 3 and a randomized, double-blind, placebo controlled, event-driven withdrawal design in Treatment Period 2

Primary Outcome

Survival analysis of time to flare in treatment period 2 (TP2) FAS2 Subjects are either ERA or JPsA

Interventions

  • OTHER placebo
  • DRUG secukinumab

Trial Details

FieldValue
Enrollment Target 86 participants
Start Date 2017-05-23
Est. Completion 2020-11-09
Phase Phase 3
Novartis Pharmaceuticals

1,375 total trials

What the finished NCT03031782 record still lists

NCT03031782 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 86 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (89% lower).

The record links to 0 conditions, and to 2 interventions - of which placebo is the first listed.

NCT03031782 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03031782 about?

NCT03031782 is a clinical study titled "Secukinumab Safety and Efficacy in Juvenile Psoriatic Arthritis (JPsA) and Enthesitis-related Arthritis (ERA)". This was a double-blind, placebo-controlled, event-driven randomized withdrawal study to investigate the efficacy and safety of secukinumab treatment in the Juvenile Idiopathic Arthritis (JIA) categories of Juvenile Psoriatic Arthritis (JPsA) and Enthesitis-related Arthritis (ERA). The study was div...

What is the current status of trial NCT03031782?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 86 participants. The study started on 2017-05-23. Estimated completion is 2020-11-09.

What interventions are being tested in trial NCT03031782?

The interventions under investigation include: placebo (OTHER), secukinumab (DRUG).

Who is sponsoring clinical trial NCT03031782?

This trial is sponsored by Novartis Pharmaceuticals, which has 1,375 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03031782's enrollment target sits among peer trials

86 1745th of 2000 higher than 254 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03031782, the US trial registry maintained by the National Library of Medicine. NCT03031782 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.