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NCT03028012 · ClinicalTrials.gov registry record · Phase 4
TPI Medication Comparison - Ketorolac, Lidocaine, or Dexamethasone
A Phase 4 study, sponsored by University of Utah.
- Terminated
- Registry status
- Phase 4
- Development phase
- 10
- Enrollment target
NCT03028012: Clinical Trial Phase 4 study, sponsored by University of Utah.
NCT03028012 is a Phase 4 study that was terminated before completion, run by University of Utah. The registered enrollment target is 10 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03028012, a Phase 4 study, was terminated before completion, sponsored by University of Utah.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 10 participants
- Enrollment target
Study Summary
Hypothesis The main hypothesis of this study is that anti-inflammatory medications (ketorolac or dexamethasone) will provide longer-lasting and greater pain relief than just lidocaine in trigger point injections where a local twitch response is evoked at the time of the injection. Purpose/Specific Aims The primary objective of this study is to compare the efficacy of three substances used in TPIs with a LTR identified at the time of the injection: a CS (dexamethasone), a NSAID (ketorolac), or only a local anesthetic (lidocaine).
Primary Outcome
Participants in this study underwent TPIs by the following method. The needle was inserted into the trigger point with the goal of eliciting a local twitch responses(LTRs). When a LTR was obtained, 0.1mL of randomized drug was injected into that location within the muscle. This was repeated until LTRs disappeared, or 1.0mL had been injected, whichever came first. This was performed in a similar manner for all affected muscles, up to a maximum of 2mL. Participants self-report their brief pain inv
Interventions
- DRUG Ketorolac
- DRUG Dexamethasone
- DRUG Lidocaine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2017-05-02 |
| Est. Completion | 2019-05-01 |
| Phase | Phase 4 |
Why NCT03028012 stopped before completion
NCT03028012 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 3 interventions - of which Ketorolac is the first listed.
NCT03028012 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03028012 about?
NCT03028012 is a clinical study titled "TPI Medication Comparison - Ketorolac, Lidocaine, or Dexamethasone". Hypothesis The main hypothesis of this study is that anti-inflammatory medications (ketorolac or dexamethasone) will provide longer-lasting and greater pain relief than just lidocaine in trigger point injections where a local twitch response is evoked at the time of the injection. Purpose/Specific...
What is the current status of trial NCT03028012?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 10 participants. The study started on 2017-05-02. Estimated completion is 2019-05-01.
What interventions are being tested in trial NCT03028012?
The interventions under investigation include: Ketorolac (DRUG), Dexamethasone (DRUG), Lidocaine (DRUG).
Who is sponsoring clinical trial NCT03028012?
This trial is sponsored by University of Utah, which has 818 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03028012's enrollment target sits among peer trials
10 1940th of 2000 higher than 33 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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