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NCT03005002 · ClinicalTrials.gov registry record · Phase 1
Durvalumab and Tremelimumab in Treating Patients With Microsatellite Stable Metastatic Colorectal Cancer to the Liver
A Phase 1 study, sponsored by City of Hope Medical Center.
- Completed
- Registry status
- Phase 1
- Development phase
- 9
- Enrollment target
NCT03005002: Completed Phase 1 study, sponsored by City of Hope Medical Center.
NCT03005002 is a Phase 1 study that has completed, run by City of Hope Medical Center. The registered enrollment target is 9 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (85% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03005002, a Phase 1 study, has completed, sponsored by City of Hope Medical Center.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 9 participants
- Enrollment target
Study Summary
This pilot clinical trial studies the side effects and how well durvalumab and tremelimumab work in treating patients with microsatellite stable colorectal cancer that has spread to the liver. Monoclonal antibodies, such as durvalumab and tremelimumab, may interfere with the ability of tumor cells to grow and spread.
Primary Outcome
Will be summarized using a 90% exact Clopper-Pearson confidence interval
Interventions
- BIOLOGICAL Durvalumab
- OTHER Laboratory Biomarker Analysis
- BIOLOGICAL Tremelimumab
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2017-06-28 |
| Est. Completion | 2019-11-26 |
| Phase | Phase 1 |
What the finished NCT03005002 record still lists
NCT03005002 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (85% lower).
The record links to 0 conditions, and to 3 interventions - of which Durvalumab is the first listed.
NCT03005002 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03005002 about?
NCT03005002 is a clinical study titled "Durvalumab and Tremelimumab in Treating Patients With Microsatellite Stable Metastatic Colorectal Cancer to the Liver". This pilot clinical trial studies the side effects and how well durvalumab and tremelimumab work in treating patients with microsatellite stable colorectal cancer that has spread to the liver. Monoclonal antibodies, such as durvalumab and tremelimumab, may interfere with the ability of tumor cells t...
What is the current status of trial NCT03005002?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 9 participants. The study started on 2017-06-28. Estimated completion is 2019-11-26.
What interventions are being tested in trial NCT03005002?
The interventions under investigation include: Durvalumab (BIOLOGICAL), Laboratory Biomarker Analysis (OTHER), Tremelimumab (BIOLOGICAL).
Who is sponsoring clinical trial NCT03005002?
This trial is sponsored by City of Hope Medical Center, which has 582 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03005002's enrollment target sits among peer trials
9 1955th of 2000 higher than 42 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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