Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT02998671 · ClinicalTrials.gov registry record · Phase 2

Study of Efficacy and Safety of CJM112 in Patients With Moderate to Severe Inflammatory Acne

A Phase 2 study, sponsored by Novartis Pharmaceuticals.

Completed
Registry status
Phase 2
Development phase
52
Enrollment target

NCT02998671: Completed Phase 2 study, sponsored by Novartis Pharmaceuticals.

NCT02998671 is a Phase 2 study that has completed, run by Novartis Pharmaceuticals. The registered enrollment target is 52 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (61% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT02998671, a Phase 2 study, has completed, sponsored by Novartis Pharmaceuticals.

COMPLETED
Registry status
Phase 2
Development phase
52 participants
Enrollment target

Study Summary

The study was designed primarily to assess preliminary efficacy and safety of CJM112 in patients with moderate to severe inflammatory acne and to determine if CJM112 has an adequate clinical profile for further clinical development. In addition, sustainability of response and dose relationship were to be explored.

Primary Outcome

Total inflammatory facial lesion count was the total count of papules, pustules and nodules assessed at day 85

Interventions

  • OTHER Placebo
  • BIOLOGICAL CJM112

Trial Details

FieldValue
Enrollment Target 52 participants
Start Date 2016-12-22
Est. Completion 2018-08-01
Phase Phase 2
Novartis Pharmaceuticals

1,375 total trials

What the finished NCT02998671 record still lists

NCT02998671 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 52 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (61% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT02998671 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02998671 about?

NCT02998671 is a clinical study titled "Study of Efficacy and Safety of CJM112 in Patients With Moderate to Severe Inflammatory Acne". The study was designed primarily to assess preliminary efficacy and safety of CJM112 in patients with moderate to severe inflammatory acne and to determine if CJM112 has an adequate clinical profile for further clinical development. In addition, sustainability of response and dose relationship were ...

What is the current status of trial NCT02998671?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 52 participants. The study started on 2016-12-22. Estimated completion is 2018-08-01.

What interventions are being tested in trial NCT02998671?

The interventions under investigation include: Placebo (OTHER), CJM112 (BIOLOGICAL).

Who is sponsoring clinical trial NCT02998671?

This trial is sponsored by Novartis Pharmaceuticals, which has 1,375 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02998671's enrollment target sits among peer trials

52 1181st of 2000 higher than 811 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02630121 · 52 participants · Phase 4

    Effect of Oxymetazoline Hydrochloride in Combination With Fluticasone Propionate on the Apnea Hypopnea Index (AHI) in Subject With Persistent Nasal Congestion and Mild Obstructive Sleep Apnea

  • NCT03629171 · 52 participants · Phase 2

    Liposome-encapsulated Daunorubicin-Cytarabine and Venetoclax in Treating Participants With Relapsed, Refractory or Untreated Acute Myeloid Leukemia

  • NCT04128748 · 52 participants · Phase 1

    Liposomal Cytarabine and Daunorubicin (CPX-351) and Quizartinib for the Treatment of Acute Myeloid Leukemia and High Risk Myelodysplastic Syndrome

  • NCT04150497 · 52 participants · Phase 1

    Phase 1/2 Study of UCART22 in Patients With Relapsed or Refractory CD22+ B-cell Acute Lymphoblastic Leukemia (BALLI-01)

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT02998671, the US trial registry maintained by the National Library of Medicine. NCT02998671 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.