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NCT02998541 · ClinicalTrials.gov registry record · Phase 3
Treatment of Adenoviral Conjunctivitis With SHP640 Compared to Povidone-iodine (PVP-I) and Placebo
A Phase 3 study, sponsored by Shire.
- Terminated
- Registry status
- Phase 3
- Development phase
- 219
- Enrollment target
NCT02998541: Clinical Trial Phase 3 study, sponsored by Shire.
NCT02998541 is a Phase 3 study that was terminated before completion, run by Shire. The registered enrollment target is 219 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (72% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02998541, a Phase 3 study, was terminated before completion, sponsored by Shire.
- TERMINATED
- Registry status
- Phase 3
- Development phase
- 219 participants
- Enrollment target
Study Summary
The purpose of this study is to determine if an investigational treatment is effective compared with placebo and PVP-Iodine in the treatment of adults and children with adenoviral conjunctivitis.
Primary Outcome
Clinical resolution of adenoviral conjunctivitis was defined as the absence (score=0) of bulbar conjunctival injection and watery conjunctival discharge in the study eye. The study eye was defined based on participant's bulbar conjunctival redness and watery conjunctival discharge scores at baseline as well as his/her cell culture-immunofluorescence assay (CC-IFA) results at baseline. Bulbar conjunctival injection was assessed based on a 0 (Normal conjunctival vascular pattern)-4 (Markedly promi
Interventions
- OTHER Placebo
- DRUG SHP640
- DRUG PVP-I 0.6%
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 219 participants |
| Start Date | 2017-03-27 |
| Est. Completion | 2019-05-13 |
| Phase | Phase 3 |
Why NCT02998541 stopped before completion
NCT02998541 is an interventional study that assigns participants to a tested intervention. The registered 219 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (72% lower).
The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.
NCT02998541 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02998541 about?
NCT02998541 is a clinical study titled "Treatment of Adenoviral Conjunctivitis With SHP640 Compared to Povidone-iodine (PVP-I) and Placebo". The purpose of this study is to determine if an investigational treatment is effective compared with placebo and PVP-Iodine in the treatment of adults and children with adenoviral conjunctivitis.
What is the current status of trial NCT02998541?
This trial is currently terminated. It is a Phase 3 study. The enrollment target is 219 participants. The study started on 2017-03-27. Estimated completion is 2019-05-13.
What interventions are being tested in trial NCT02998541?
The interventions under investigation include: Placebo (OTHER), SHP640 (DRUG), PVP-I 0.6% (DRUG).
Who is sponsoring clinical trial NCT02998541?
This trial is sponsored by Shire, which has 245 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02998541's enrollment target sits among peer trials
219 1329th of 2000 higher than 670 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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