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NCT02986984 · ClinicalTrials.gov registry record

Transformative Research in Diabetic Nephropathy

A clinical trial of Diabetic Nephropathies and Diabetic Glomerulosclerosis, sponsored by University of Pennsylvania.

Recruiting
Registry status
400
Enrollment target
17
Study locations

NCT02986984 is a study of Diabetic Nephropathies and Diabetic Glomerulosclerosis that is actively recruiting participants, run by University of Pennsylvania. The registered enrollment target is 400 participants, above the 94-participant average among 12 other Diabetic Nephropathies trials with a reported enrollment target (326% higher). The trial reports 17 study locations across 13 states.

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The verdict

NCT02986984, a study of Diabetic Nephropathies and Diabetic Glomerulosclerosis, is actively recruiting participants, sponsored by University of Pennsylvania.

RECRUITING
Registry status
400 participants
Enrollment target
17
Study locations

Study Summary

This is a prospective, observational, cohort study of patients with a clinical diagnosis of diabetes who are undergoing clinically indicated kidney biopsy. The intent is to collect, process, and study kidney tissue and to harvest blood, urine and genetic materials to elucidate molecular pathways and link them to biomarkers that characterize those patients have a rapid decline in kidney function (\> 5 mL/min/1.73m2/year) from those with lesser degrees of kidney function change over the period of observation. High through-put genomic analysis associated with genetic and biomarker testing will serve to identify key potential therapeutic targets for DKD by comparing patients with rapid and slow progression patterns. Each participating clinical site will search for, consent, harvest the biopsy sample, and enroll the participants as required for the TRIDENT protocol.

Interventions

  • OTHER There is no intervention

Study Locations (17)

New York

  • Mount Sinai Hospital - New York
  • Columbia University - New York
  • Albert Einstein College of Medicine - The Bronx

California

  • University of Southern California - Los Angeles
  • Stanford University - Palo Alto

Pennsylvania

  • Lehigh Valley Health Network - Allentown
  • University of Pennsylvania - Philadelphia

Arkansas

  • University of Arkansas for Medical Sciences - Little Rock

Connecticut

  • Yale University - New Haven

Illinois

  • Northwestern University - Chicago

Michigan

  • University of Michigan - Ann Arbor

New Mexico

  • University of New Mexico - Albuquerque

Trial Details

FieldValue
Enrollment Target 400 participants
Start Date 2016-12
Est. Completion 2027-06

Sponsor

University of Pennsylvania

1,423 total trials

What the Registry Record Tells You About NCT02986984

The ClinicalTrials.gov registry entry for NCT02986984 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 400 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 94-participant average among 12 other Diabetic Nephropathies trials with a reported enrollment target (326% higher). The listed sponsor is University of Pennsylvania, which has 1,423 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Diabetic Nephropathies appearing as the primary indexed condition, and to 1 intervention - of which There is no intervention is the first listed.

NCT02986984 reports 17 study locations spanning 13 distinct geographic areas - top geographies include New York, California, Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT02986984 about?

NCT02986984 is a clinical study titled "Transformative Research in Diabetic Nephropathy". This is a prospective, observational, cohort study of patients with a clinical diagnosis of diabetes who are undergoing clinically indicated kidney biopsy. The intent is to collect, process, and study kidney tissue and to harvest blood, urine and genetic materials to elucidate molecular pathways and...

What is the current status of trial NCT02986984?

This trial is currently recruiting. The enrollment target is 400 participants. The study started on 2016-12. Estimated completion is 2027-06.

What conditions does trial NCT02986984 study?

This clinical trial studies the following conditions: Diabetic Nephropathies, Diabetic Glomerulosclerosis.

What interventions are being tested in trial NCT02986984?

The interventions under investigation include: There is no intervention (OTHER).

Who is sponsoring clinical trial NCT02986984?

This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02986984 being conducted?

This trial has 17 study locations across Arkansas, California, Connecticut, Illinois, Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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