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NCT02980068 · ClinicalTrials.gov registry record · Phase 1
A Study of Oral Nitrate in Adults With Pulmonary Hypertension With Heart Failure and Preserved Ejection Fraction
A Phase 1 study, sponsored by Gladwin, Mark, MD.
- Completed
- Registry status
- Phase 1
- Development phase
- 77
- Enrollment target
NCT02980068: Completed Phase 1 study, sponsored by Gladwin, Mark, MD.
NCT02980068 is a Phase 1 study that has completed, run by Gladwin, Mark, MD. The registered enrollment target is 77 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (28% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02980068, a Phase 1 study, has completed, sponsored by Gladwin, Mark, MD.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 77 participants
- Enrollment target
Study Summary
This is an open-label, single-center study to examine distinguishing features of the structure and function of the oral and gut microbiome in healthy adult normal volunteers compared to volunteers with PH-HFpEF in the breakdown of oral nitrate.
Primary Outcome
The investigators will examine urine nitrate
Interventions
- DRUG 15N Nitrate
- DRUG 14N Nitrate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 77 participants |
| Start Date | 2017-08-28 |
| Est. Completion | 2022-02-25 |
| Phase | Phase 1 |
What the finished NCT02980068 record still lists
NCT02980068 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 77 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (28% higher).
The record links to 0 conditions, and to 2 interventions - of which 15N Nitrate is the first listed.
NCT02980068 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02980068 about?
NCT02980068 is a clinical study titled "A Study of Oral Nitrate in Adults With Pulmonary Hypertension With Heart Failure and Preserved Ejection Fraction". This is an open-label, single-center study to examine distinguishing features of the structure and function of the oral and gut microbiome in healthy adult normal volunteers compared to volunteers with PH-HFpEF in the breakdown of oral nitrate.
What is the current status of trial NCT02980068?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 77 participants. The study started on 2017-08-28. Estimated completion is 2022-02-25.
What interventions are being tested in trial NCT02980068?
The interventions under investigation include: 15N Nitrate (DRUG), 14N Nitrate (DRUG).
Who is sponsoring clinical trial NCT02980068?
This trial is sponsored by Gladwin, Mark, MD, which has 11 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02980068's enrollment target sits among peer trials
77 703rd of 2000 higher than 1,296 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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