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NCT02964741 · ClinicalTrials.gov registry record · NA
Investigation and Modulation of the Mu-Opioid Mechanisms in Migraine (in Vivo)
A NA study, sponsored by University of Michigan.
- Terminated
- Registry status
- NA
- Development phase
- 44
- Enrollment target
NCT02964741: Clinical Trial NA study, sponsored by University of Michigan.
NCT02964741 is a NA study that was terminated before completion, run by University of Michigan. The registered enrollment target is 44 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02964741, a NA study, was terminated before completion, sponsored by University of Michigan.
- TERMINATED
- Registry status
- NA
- Development phase
- 44 participants
- Enrollment target
Study Summary
This study investigates whether non-invasive brain stimulation, given for 20 minutes/once per day for ten days (M-F) can reduce migraine pain. Thirty patients will receive this treatment, while thirty will receive a "sham" procedure. Up to thirty healthy volunteers will be asked to undergo baseline assessments only (imaging, but no brain stimulation). Healthy volunteer data may be used from a prior study (NINDS-K23062946 project \[IRBMED #HUM00027383; Dr. Alexandre DaSilva, Principal Investigator\]).
Primary Outcome
Moderate to severe headache is defined by the pain over 3 in an Numeric Rating Scale (NRS) ranging from 0 to 10 between end of treatment and one month follow-up.
Interventions
- DEVICE Sham Comparator
- DEVICE Active Comparator
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 44 participants |
| Start Date | 2017-02-22 |
| Est. Completion | 2021-08-01 |
| Phase | NA |
Why NCT02964741 stopped before completion
NCT02964741 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 44 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which Sham Comparator is the first listed.
NCT02964741 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02964741 about?
NCT02964741 is a clinical study titled "Investigation and Modulation of the Mu-Opioid Mechanisms in Migraine (in Vivo)". This study investigates whether non-invasive brain stimulation, given for 20 minutes/once per day for ten days (M-F) can reduce migraine pain. Thirty patients will receive this treatment, while thirty will receive a "sham" procedure. Up to thirty healthy volunteers will be asked to undergo baseline ...
What is the current status of trial NCT02964741?
This trial is currently terminated. It is a NA study. The enrollment target is 44 participants. The study started on 2017-02-22. Estimated completion is 2021-08-01.
What interventions are being tested in trial NCT02964741?
The interventions under investigation include: Sham Comparator (DEVICE), Active Comparator (DEVICE).
Who is sponsoring clinical trial NCT02964741?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02964741's enrollment target sits among peer trials
44 1423rd of 2000 higher than 566 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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