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NCT02954198 · ClinicalTrials.gov registry record · NA

Once-daily Regimen With Envarsus® to Optimize Immunosuppression Management and Outcomes in Kidney Transplant Recipients

A NA study, sponsored by Medical University of South Carolina.

Completed
Registry status
NA
Development phase
40
Enrollment target

NCT02954198: Completed NA study, sponsored by Medical University of South Carolina.

NCT02954198 is a NA study that has completed, run by Medical University of South Carolina. The registered enrollment target is 40 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02954198, a NA study, has completed, sponsored by Medical University of South Carolina.

COMPLETED
Registry status
NA
Development phase
40 participants
Enrollment target

Study Summary

With the availability of well-studied once-daily formulations of tacrolimus, the ability to achieve a true once-daily immunosuppressant regimen along with everolimus and steroids may finally be achievable and have the potential to optimize immunosuppression safety and efficacy in kidney transplantation.

Primary Outcome

Percent of subjects reporting high medication adherence at baseline compared to 6 months post-conversion, using the Morisky Medication Adherence scale (MMAS). The MMAS rates medication adherence on a scale of 0 to 8. 0 is high adherence, 1-2 is medium adherence, and greater than or equal to 3 is low adherence.

Interventions

  • DRUG Everolimus
  • DRUG Prednisone
  • DRUG Tacrolimus
  • DRUG Mycophenolate mofetil

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2016-12-01
Est. Completion 2018-12-27
Phase NA

What the finished NCT02954198 record still lists

NCT02954198 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).

The record links to 0 conditions, and to 4 interventions - of which Everolimus is the first listed.

NCT02954198 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02954198 about?

NCT02954198 is a clinical study titled "Once-daily Regimen With Envarsus® to Optimize Immunosuppression Management and Outcomes in Kidney Transplant Recipients". With the availability of well-studied once-daily formulations of tacrolimus, the ability to achieve a true once-daily immunosuppressant regimen along with everolimus and steroids may finally be achievable and have the potential to optimize immunosuppression safety and efficacy in kidney transplantat...

What is the current status of trial NCT02954198?

This trial is currently completed. It is a NA study. The enrollment target is 40 participants. The study started on 2016-12-01. Estimated completion is 2018-12-27.

What interventions are being tested in trial NCT02954198?

The interventions under investigation include: Everolimus (DRUG), Prednisone (DRUG), Tacrolimus (DRUG), Mycophenolate mofetil (DRUG).

Who is sponsoring clinical trial NCT02954198?

This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02954198's enrollment target sits among peer trials

40 1447th of 2000 higher than 465 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02954198, the US trial registry maintained by the National Library of Medicine. NCT02954198 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.