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NCT02953782 · ClinicalTrials.gov registry record · Phase 1

Study of Magrolimab (Hu5F9-G4) in Combination With Cetuximab in Participants With Solid Tumors and Advanced Colorectal Cancer

A Phase 1 study, sponsored by Gilead Sciences.

Completed
Registry status
Phase 1
Development phase
78
Enrollment target

NCT02953782 is a Phase 1 study that has completed, run by Gilead Sciences. The registered enrollment target is 78 participants.

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The verdict

NCT02953782, a Phase 1 study, has completed, sponsored by Gilead Sciences.

COMPLETED
Registry status
Phase 1
Development phase
78 participants
Enrollment target

Study Summary

The primary objectives of this study are: (Phase 1b) to investigate the safety and tolerability and to determine the recommended Phase 2 dose (RP2D) for magrolimab in combination with cetuximab; and (Phase 2) to evaluate overall response rate (ORR) of magrolimab in combination with cetuximab in participants with Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) mutant and KRAS wild-type colorectal cancer (CRC).

Interventions

  • DRUG Cetuximab
  • DRUG Magrolimab

Trial Details

FieldValue
Enrollment Target 78 participants
Start Date 2016-11-02
Est. Completion 2020-02-10
Phase Phase 1

Sponsor

Gilead Sciences

504 total trials

What the Registry Record Tells You About NCT02953782

The ClinicalTrials.gov registry entry for NCT02953782 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 78 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Gilead Sciences, which has 504 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Cetuximab is the first listed.

NCT02953782 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02953782 about?

NCT02953782 is a clinical study titled "Study of Magrolimab (Hu5F9-G4) in Combination With Cetuximab in Participants With Solid Tumors and Advanced Colorectal Cancer". The primary objectives of this study are: (Phase 1b) to investigate the safety and tolerability and to determine the recommended Phase 2 dose (RP2D) for magrolimab in combination with cetuximab; and (Phase 2) to evaluate overall response rate (ORR) of magrolimab in combination with cetuximab in part...

What is the current status of trial NCT02953782?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 78 participants. The study started on 2016-11-02. Estimated completion is 2020-02-10.

What interventions are being tested in trial NCT02953782?

The interventions under investigation include: Cetuximab (DRUG), Magrolimab (DRUG).

Who is sponsoring clinical trial NCT02953782?

This trial is sponsored by Gilead Sciences, which has 504 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.