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NCT02953587 · ClinicalTrials.gov registry record · Phase 1
Effect of Ghrelin on Glucose Metabolism After Bariatric Surgery
A Phase 1 study, sponsored by Vanderbilt University Medical Center.
- Completed
- Registry status
- Phase 1
- Development phase
- 70
- Enrollment target
NCT02953587: Completed Phase 1 study, sponsored by Vanderbilt University Medical Center.
NCT02953587 is a Phase 1 study that has completed, run by Vanderbilt University Medical Center. The registered enrollment target is 70 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (17% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02953587, a Phase 1 study, has completed, sponsored by Vanderbilt University Medical Center.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 70 participants
- Enrollment target
Study Summary
The purpose of this study is to determine if the altered nutrient exposure to the GI tract after bariatric surgery reveals a negative incretin effect of ghrelin.
Primary Outcome
The objective for this protocol is to determine if ghrelin infusion worsens glucose tolerance during jejunal administration of glucose and if the response is difference after bariatric surgery (RYGB or VSG).
Interventions
- DRUG Saline
- PROCEDURE Oral Glucose Tolerance Test (OGTT)
- DRUG Human Ghrelin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2016-09 |
| Est. Completion | 2023-01-30 |
| Phase | Phase 1 |
What the finished NCT02953587 record still lists
NCT02953587 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 70 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (17% higher).
The record links to 0 conditions, and to 3 interventions - of which Saline is the first listed.
NCT02953587 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02953587 about?
NCT02953587 is a clinical study titled "Effect of Ghrelin on Glucose Metabolism After Bariatric Surgery". The purpose of this study is to determine if the altered nutrient exposure to the GI tract after bariatric surgery reveals a negative incretin effect of ghrelin.
What is the current status of trial NCT02953587?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 70 participants. The study started on 2016-09. Estimated completion is 2023-01-30.
What interventions are being tested in trial NCT02953587?
The interventions under investigation include: Saline (DRUG), Oral Glucose Tolerance Test (OGTT) (PROCEDURE), Human Ghrelin (DRUG).
Who is sponsoring clinical trial NCT02953587?
This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02953587's enrollment target sits among peer trials
70 749th of 2000 higher than 1,227 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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