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NCT02950883 · ClinicalTrials.gov registry record · Phase 2
Saline Hypertonic in Preschoolers + CT
A Phase 2 study, sponsored by University of Washington, the Collaborative Health Studies Coordinating Center.
- Completed
- Registry status
- Phase 2
- Development phase
- 116
- Enrollment target
NCT02950883: Completed Phase 2 study, sponsored by University of Washington, the Collaborative Health Studies Coordinating Center.
NCT02950883 is a Phase 2 study that has completed, run by University of Washington, the Collaborative Health Studies Coordinating Center. The registered enrollment target is 116 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (13% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02950883, a Phase 2 study, has completed, sponsored by University of Washington, the Collaborative Health Studies Coordinating Center.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 116 participants
- Enrollment target
Study Summary
The purpose of this study is to assess whether inhalation of 7% hypertonic saline (HS) twice daily for 48 weeks reduces structural lung disease as assessed by computed tomography (CT) in comparison with inhalation of 0.9% isotonic saline (IS) in preschool children (ages 3 to 6) with cystic fibrosis.
Primary Outcome
The difference in PRAGMA-CF %Dis between HS and IS study arm at end of study (48 weeks), adjusted for baseline, measured from standardized chest CT.
Interventions
- DRUG Active Treatment Group 7% Hypertonic Saline
- DRUG Control Group 0.9% Isotonic Saline
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 116 participants |
| Start Date | 2015-03-24 |
| Est. Completion | 2021-06-25 |
| Phase | Phase 2 |
Sponsor
University of Washington, the Collaborative Health Studies Coordinating Center5 total trials
What the finished NCT02950883 record still lists
NCT02950883 is an interventional study that assigns participants to a tested intervention. The registered 116 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (13% lower).
The record links to 0 conditions, and to 2 interventions - of which Active Treatment Group 7% Hypertonic Saline is the first listed.
NCT02950883 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02950883 about?
NCT02950883 is a clinical study titled "Saline Hypertonic in Preschoolers + CT". The purpose of this study is to assess whether inhalation of 7% hypertonic saline (HS) twice daily for 48 weeks reduces structural lung disease as assessed by computed tomography (CT) in comparison with inhalation of 0.9% isotonic saline (IS) in preschool children (ages 3 to 6) with cystic fibrosis.
What is the current status of trial NCT02950883?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 116 participants. The study started on 2015-03-24. Estimated completion is 2021-06-25.
What interventions are being tested in trial NCT02950883?
The interventions under investigation include: Active Treatment Group 7% Hypertonic Saline (DRUG), Control Group 0.9% Isotonic Saline (DRUG).
Who is sponsoring clinical trial NCT02950883?
This trial is sponsored by University of Washington, the Collaborative Health Studies Coordinating Center, which has 5 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02950883's enrollment target sits among peer trials
116 623rd of 2000 higher than 1,375 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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