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NCT02950480 · ClinicalTrials.gov registry record · Phase 2
Breast Capsular Contracture Following Post-Mastectomy Reconstruction in Women Treated With the Leukotriene Inhibitor Zafirlukast: A Phase II Trial
A Phase 2 study, sponsored by University of California, San Francisco.
- Terminated
- Registry status
- Phase 2
- Development phase
- 4
- Enrollment target
NCT02950480: Clinical Trial Phase 2 study, sponsored by University of California, San Francisco.
NCT02950480 is a Phase 2 study that was terminated before completion, run by University of California, San Francisco. The registered enrollment target is 4 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02950480, a Phase 2 study, was terminated before completion, sponsored by University of California, San Francisco.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 4 participants
- Enrollment target
Study Summary
A 2 arm, 90 patient (45 per cohort) trial in patients with breast cancer who will be undergoing mastectomy with immediate tissue-expander reconstruction to determine whether treatment with zafirlukast (20mg PO BID) can reduce or prevent the development of capsular contracture.
Primary Outcome
Compare capsular thickness by gross and microscopic measurement at the time of expander-implant exchange in those treated with zafirlukast (20 mg PO BID) compared with standard of care.
Interventions
- DRUG zafirlukast
- OTHER Standard of Care (no intervention)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2017-03-13 |
| Est. Completion | 2018-12-20 |
| Phase | Phase 2 |
Why NCT02950480 stopped before completion
NCT02950480 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which zafirlukast is the first listed.
NCT02950480 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02950480 about?
NCT02950480 is a clinical study titled "Breast Capsular Contracture Following Post-Mastectomy Reconstruction in Women Treated With the Leukotriene Inhibitor Zafirlukast: A Phase II Trial". A 2 arm, 90 patient (45 per cohort) trial in patients with breast cancer who will be undergoing mastectomy with immediate tissue-expander reconstruction to determine whether treatment with zafirlukast (20mg PO BID) can reduce or prevent the development of capsular contracture.
What is the current status of trial NCT02950480?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 4 participants. The study started on 2017-03-13. Estimated completion is 2018-12-20.
What interventions are being tested in trial NCT02950480?
The interventions under investigation include: zafirlukast (DRUG), Standard of Care (no intervention) (OTHER).
Who is sponsoring clinical trial NCT02950480?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02950480's enrollment target sits among peer trials
4 2001st of 2000 the lowest of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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