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NCT02949219 · ClinicalTrials.gov registry record · Phase 2

Pembrolizumab in Treating Patients With Small Bowel Adenocarcinoma That is Metastatic or Locally Advanced and Cannot Be Removed by Surgery

A Phase 2 study of Metastatic Small Intestinal Adenocarcinoma and Recurrent Small Intestinal Carcinoma, sponsored by Academic and Community Cancer Research United.

Active
Registry status
Phase 2
Development phase
41
Enrollment target
8
Study locations

NCT02949219: Active Phase 2 study of Metastatic Small Intestinal Adenocarcinoma and Recurrent Small Intestinal Carcinoma, sponsored by Academic and Community Cancer Research United.

NCT02949219 is a Phase 2 study of Metastatic Small Intestinal Adenocarcinoma and Recurrent Small Intestinal Carcinoma that is active but no longer recruiting, run by Academic and Community Cancer Research United. The registered enrollment target is 41 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (69% lower). The trial reports 8 study locations across 7 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02949219, a Phase 2 study of Metastatic Small Intestinal Adenocarcinoma and Recurrent Small Intestinal Carcinoma, is active but no longer recruiting, sponsored by Academic and Community Cancer Research United.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
41 participants
Enrollment target
8
Study locations

Study Summary

This phase II trial studies how well pembrolizumab works in treating patients with small bowel adenocarcinoma that has spread to other places in the body or that cannot be removed by surgery. Monoclonal antibodies, such as pembrolizumab, may interfere with the ability of tumor cells to grow and spread.

Interventions

  • BIOLOGICAL Pembrolizumab
  • OTHER Laboratory Biomarker Analysis

Study Locations (8)

Arizona

  • Mayo Clinic Hospital - Phoenix
  • Mayo Clinic in Arizona - Scottsdale

District of Columbia

  • MedStar Georgetown University Hospital - Washington D.C.

Minnesota

  • Mayo Clinic - Rochester

Missouri

  • Washington University School of Medicine - St Louis

New York

  • Roswell Park Cancer Institute - Buffalo

South Dakota

  • Rapid City Regional Hospital - Rapid City

Texas

  • M D Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 41 participants
Start Date 2017-03-24
Est. Completion 2024-12-31
Phase Phase 2

What the registry record for NCT02949219 still lists

NCT02949219 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 41 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (69% lower).

The record links to 3 conditions, with Metastatic Small Intestinal Adenocarcinoma appearing as the primary indexed condition, and to 2 interventions - of which Pembrolizumab is the first listed.

NCT02949219 lists 8 locations in 7 states (Arizona, District of Columbia, Minnesota).

Frequently Asked Questions

What is clinical trial NCT02949219 about?

NCT02949219 is a clinical study titled "Pembrolizumab in Treating Patients With Small Bowel Adenocarcinoma That is Metastatic or Locally Advanced and Cannot Be Removed by Surgery". This phase II trial studies how well pembrolizumab works in treating patients with small bowel adenocarcinoma that has spread to other places in the body or that cannot be removed by surgery. Monoclonal antibodies, such as pembrolizumab, may interfere with the ability of tumor cells to grow and spre...

What is the current status of trial NCT02949219?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 41 participants. The study started on 2017-03-24. Estimated completion is 2024-12-31.

What conditions does trial NCT02949219 study?

This clinical trial studies the following conditions: Metastatic Small Intestinal Adenocarcinoma, Recurrent Small Intestinal Carcinoma, Unresectable Small Intestinal Carcinoma.

What interventions are being tested in trial NCT02949219?

The interventions under investigation include: Pembrolizumab (BIOLOGICAL), Laboratory Biomarker Analysis (OTHER).

Who is sponsoring clinical trial NCT02949219?

This trial is sponsored by Academic and Community Cancer Research United, which has 42 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02949219 being conducted?

This trial has 8 study locations across Arizona, District of Columbia, Minnesota, Missouri, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Metastatic Small Intestinal Adenocarcinoma

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT02949219's enrollment target sits among peer trials

41 1352nd of 2000 higher than 639 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02949219, the US trial registry maintained by the National Library of Medicine. NCT02949219 (small enrollment · multi site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.