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NCT02939352 · ClinicalTrials.gov registry record · Early Phase 1

The Effects of Theta Burst Stimulation on the Brain Response to Drug and Alcohol Cues

A Early Phase 1 study, sponsored by Medical University of South Carolina.

Completed
Registry status
Early Phase 1
Development phase
49
Enrollment target

NCT02939352 is a Early Phase 1 study that has completed, run by Medical University of South Carolina. The registered enrollment target is 49 participants.

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The verdict

NCT02939352, a Early Phase 1 study, has completed, sponsored by Medical University of South Carolina.

COMPLETED
Registry status
Early Phase 1
Development phase
49 participants
Enrollment target

Study Summary

High relapse rates among substance dependent individuals are likely due to a combination of factors that involve limbic circuits in the brain involved in craving, including vulnerability to salient cues. Emerging data suggests that non-invasive, targeted brain stimulation may be able to modulate activity in these circuits and decrease craving. The primary goal of this pilot study is to determine the extent to which a single session of continuous theta burst stimulation to the medial prefrontal cortex can attenuate limbic circuitry involved in craving among cocaine users and alcohol users. This will be tested through a double-blind,sham-controlled brain stimulation and brain imaging study in a cohort of polysubstance abusers and alcohol users.

Interventions

  • DEVICE Real continuous Theta Burst Stimulation
  • DEVICE Sham continuous Theta Burst Stimulation

Trial Details

FieldValue
Enrollment Target 49 participants
Start Date 2014-09
Est. Completion 2015-12
Phase Early Phase 1

What the Registry Record Tells You About NCT02939352

The ClinicalTrials.gov registry entry for NCT02939352 describes a study currently listed as completed, categorized as Early Phase 1. The registered enrollment target is 49 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Medical University of South Carolina, which has 755 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Real continuous Theta Burst Stimulation is the first listed.

NCT02939352 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02939352 about?

NCT02939352 is a clinical study titled "The Effects of Theta Burst Stimulation on the Brain Response to Drug and Alcohol Cues". High relapse rates among substance dependent individuals are likely due to a combination of factors that involve limbic circuits in the brain involved in craving, including vulnerability to salient cues. Emerging data suggests that non-invasive, targeted brain stimulation may be able to modulate act...

What is the current status of trial NCT02939352?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 49 participants. The study started on 2014-09. Estimated completion is 2015-12.

What interventions are being tested in trial NCT02939352?

The interventions under investigation include: Real continuous Theta Burst Stimulation (DEVICE), Sham continuous Theta Burst Stimulation (DEVICE).

Who is sponsoring clinical trial NCT02939352?

This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.