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NCT02939313 · ClinicalTrials.gov registry record · Early Phase 1

Cortical rTMS as a Tool to Change Brain Reactivity to Alcohol Cues

A Early Phase 1 study, sponsored by Medical University of South Carolina.

Completed
Registry status
Early Phase 1
Development phase
71
Enrollment target

NCT02939313: Completed Early Phase 1 study, sponsored by Medical University of South Carolina.

NCT02939313 is a Early Phase 1 study that has completed, run by Medical University of South Carolina. The registered enrollment target is 71 participants, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (34% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02939313, a Early Phase 1 study, has completed, sponsored by Medical University of South Carolina.

COMPLETED
Registry status
Early Phase 1
Development phase
71 participants
Enrollment target

Study Summary

The goal of this investigation is to determine if, in heavy alcohol users, a single session of transcranial magnetic brain stimulation (TMS) over a brain region involved in craving (medial prefrontal cortex) and a brain region involved in cogntive control (dorsolateral prefrontal cortex) can lower an individual's craving and brain response to alcohol cues. This study involves a screening visit, followed by three visits which involve brain imaging (using functional MRI) and brain stimulation (using TMS). There is also an additional Magnetic resonance spectroscopy (MRS) exploratory Aim in which we will measure the concentration of glutamate in the prefrontal cortex before and after a session of TMS.

Interventions

  • DEVICE sham
  • DEVICE medial prefrontal cortex
  • DEVICE dorsolateral prefrontal cortex

Trial Details

FieldValue
Enrollment Target 71 participants
Start Date 2016-01
Est. Completion 2021-04-12
Phase Early Phase 1

What the finished NCT02939313 record still lists

NCT02939313 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 71 participants, a relatively small participant target, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (34% higher).

The record links to 0 conditions, and to 3 interventions - of which sham is the first listed.

NCT02939313 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02939313 about?

NCT02939313 is a clinical study titled "Cortical rTMS as a Tool to Change Brain Reactivity to Alcohol Cues". The goal of this investigation is to determine if, in heavy alcohol users, a single session of transcranial magnetic brain stimulation (TMS) over a brain region involved in craving (medial prefrontal cortex) and a brain region involved in cogntive control (dorsolateral prefrontal cortex) can lower a...

What is the current status of trial NCT02939313?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 71 participants. The study started on 2016-01. Estimated completion is 2021-04-12.

What interventions are being tested in trial NCT02939313?

The interventions under investigation include: sham (DEVICE), medial prefrontal cortex (DEVICE), dorsolateral prefrontal cortex (DEVICE).

Who is sponsoring clinical trial NCT02939313?

This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02939313's enrollment target sits among peer trials

71 328th of 2000 higher than 1,663 of 2,000 other Early Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02939313, the US trial registry maintained by the National Library of Medicine. NCT02939313 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.