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NCT02939183 · ClinicalTrials.gov registry record · Phase 1
Phase 1b Study Evaluating OPomD in Relapsed or Refractory Multiple Myeloma
A Phase 1 study, sponsored by Amgen.
- Completed
- Registry status
- Phase 1
- Development phase
- 61
- Enrollment target
NCT02939183: Completed Phase 1 study, sponsored by Amgen.
NCT02939183 is a Phase 1 study that has completed, run by Amgen. The registered enrollment target is 61 participants, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02939183, a Phase 1 study, has completed, sponsored by Amgen.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 61 participants
- Enrollment target
Study Summary
A study evaluating two new formulations of oprozomib plus pomalidomide and dexamethasone in participants with relapsed refractory multiple myeloma.
Primary Outcome
DLTs were graded using the Common Terminology Criteria for Adverse Events (CTCAE) version 4.03 and included the below, if judged by the investigator/medical monitor to be possibly related to study treatment: Non-hematologic DLTs were any ≥ Grade 3 toxicity, except: Grade 3 asymptomatic electrolyte abnormalities (except hypophosphatemia \> 24 hours); Grade 3 nausea, vomiting and diarrhea \< 3 days; Grade 3 fatigue \< 14 days; ≥ Grade 3 hyperglycemia/toxicity due to dexamethasone; ≥ Grade 3 rash d
Interventions
- DRUG Dexamethasone
- DRUG Pomalidomide
- DRUG Immediate Release (IR) Formulation
- DRUG Gastro-Retentive (GR) Formulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 61 participants |
| Start Date | 2017-01-17 |
| Est. Completion | 2022-10-06 |
| Phase | Phase 1 |
What the finished NCT02939183 record still lists
NCT02939183 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 61 participants, a relatively small participant target, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target.
The record links to 0 conditions, and to 4 interventions - of which Dexamethasone is the first listed.
NCT02939183 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02939183 about?
NCT02939183 is a clinical study titled "Phase 1b Study Evaluating OPomD in Relapsed or Refractory Multiple Myeloma". A study evaluating two new formulations of oprozomib plus pomalidomide and dexamethasone in participants with relapsed refractory multiple myeloma.
What is the current status of trial NCT02939183?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 61 participants. The study started on 2017-01-17. Estimated completion is 2022-10-06.
What interventions are being tested in trial NCT02939183?
The interventions under investigation include: Dexamethasone (DRUG), Pomalidomide (DRUG), Immediate Release (IR) Formulation (DRUG), Gastro-Retentive (GR) Formulation (DRUG).
Who is sponsoring clinical trial NCT02939183?
This trial is sponsored by Amgen, which has 558 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02939183's enrollment target sits among peer trials
61 828th of 2000 higher than 1,170 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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