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NCT02934451 · ClinicalTrials.gov registry record
Dental Malocclusion and Craniofacial Development in OI
A clinical trial of Osteogenesis Imperfecta, sponsored by Baylor College of Medicine.
- Active
- Registry status
- 75
- Enrollment target
- 3
- Study locations
NCT02934451: Active study of Osteogenesis Imperfecta, sponsored by Baylor College of Medicine.
NCT02934451 is a study of Osteogenesis Imperfecta that is active but no longer recruiting, run by Baylor College of Medicine. The registered enrollment target is 75 participants, below the 155-participant average among 13 other Osteogenesis Imperfecta trials with a reported enrollment target (52% lower). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02934451, a study of Osteogenesis Imperfecta, is active but no longer recruiting, sponsored by Baylor College of Medicine.
- ACTIVE NOT RECRUITING
- Registry status
- 75 participants
- Enrollment target
- 3
- Study locations
Study Summary
Osteogenesis imperfecta (OI) is a rare inherited disorder that causes bones to break easily. Individuals with osteogenesis imperfecta break bones often and may have other problems, including hearing loss and pain and difficulty getting around. People with moderate to severe OI may also be diagnosed with dentinogenesis imperfecta (DI). DI is characterized by grey or brown teeth that may chip and wear down and break easily. People with DI may also have skull and neck defects. These patients may have severe teeth misalignment resulting in clinically significant chewing problems. Teeth misalignment in OI is very hard to treat because of the quality and quantity of bone. The overall goal of this study is to improve dental health to improve the quality of life of people with OI.
Primary Outcome
Measure teeth misalignment in individuals with moderate to severe OI using scans of the teeth.
Conditions Studied
Study Locations (3)
California
- University of California Los Angeles - Los Angeles
Texas
- Baylor College of Medicine - Houston
Quebec
- Shriners Hospital for Children - Montreal
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2016-08 |
| Est. Completion | 2027-12 |
What the registry record for NCT02934451 still lists
NCT02934451 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 75 participants, a relatively small participant target, below the 155-participant average among 13 other Osteogenesis Imperfecta trials with a reported enrollment target (52% lower).
The record links to 1 condition, with Osteogenesis Imperfecta appearing as the primary indexed condition, and to 0 interventions.
NCT02934451 reports a single indexed study location in California, Texas, Quebec.
Frequently Asked Questions
What is clinical trial NCT02934451 about?
NCT02934451 is a clinical study titled "Dental Malocclusion and Craniofacial Development in OI". Osteogenesis imperfecta (OI) is a rare inherited disorder that causes bones to break easily. Individuals with osteogenesis imperfecta break bones often and may have other problems, including hearing loss and pain and difficulty getting around. People with moderate to severe OI may also be diagnosed ...
What is the current status of trial NCT02934451?
This trial is currently active not recruiting. The enrollment target is 75 participants. The study started on 2016-08. Estimated completion is 2027-12.
What conditions does trial NCT02934451 study?
This clinical trial studies the following conditions: Osteogenesis Imperfecta.
Who is sponsoring clinical trial NCT02934451?
This trial is sponsored by Baylor College of Medicine, which has 616 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02934451 being conducted?
This trial has 3 study locations across California, Texas, Quebec. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Osteogenesis Imperfecta
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02934451's enrollment target sits among peer trials
75 8th of 13 higher than 6 of 13 other Osteogenesis Imperfecta trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Osteogenesis Imperfecta trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
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Clear Aligners for the Treatment of Dental Malocclusion in OI
ACTIVE NOT RECRUITING · NA
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