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NCT02932410 · ClinicalTrials.gov registry record · Phase 3
A Study to Assess Whether Macitentan Delays Disease Progression in Children With Pulmonary Arterial Hypertension (PAH)
A Phase 3 study, sponsored by Actelion.
- Completed
- Registry status
- Phase 3
- Development phase
- 165
- Enrollment target
NCT02932410: Completed Phase 3 study, sponsored by Actelion.
NCT02932410 is a Phase 3 study that has completed, run by Actelion. The registered enrollment target is 165 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (79% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02932410, a Phase 3 study, has completed, sponsored by Actelion.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 165 participants
- Enrollment target
Study Summary
This is a prospective, multicenter, open-label, randomized, controlled, parallel Phase 3 study with an open-label single-arm extension period to evaluate pharmacokinetics (PK), safety and efficacy of macitentan in children with pulmonary arterial hypertension (PAH).
Primary Outcome
Observed steady-state trough (pre-dose) plasma concentration of macitentan and aprocitentan (active metabolite) at Week 12 based on body weight were reported. This outcome measure was planned to be analyzed for specified arms only.
Interventions
- DRUG Macitentan
- OTHER Standard-of-care
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 165 participants |
| Start Date | 2017-10-24 |
| Est. Completion | 2025-11-27 |
| Phase | Phase 3 |
What the finished NCT02932410 record still lists
NCT02932410 is an interventional study that assigns participants to a tested intervention. The registered 165 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (79% lower).
The record links to 0 conditions, and to 2 interventions - of which Macitentan is the first listed.
NCT02932410 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02932410 about?
NCT02932410 is a clinical study titled "A Study to Assess Whether Macitentan Delays Disease Progression in Children With Pulmonary Arterial Hypertension (PAH)". This is a prospective, multicenter, open-label, randomized, controlled, parallel Phase 3 study with an open-label single-arm extension period to evaluate pharmacokinetics (PK), safety and efficacy of macitentan in children with pulmonary arterial hypertension (PAH).
What is the current status of trial NCT02932410?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 165 participants. The study started on 2017-10-24. Estimated completion is 2025-11-27.
What interventions are being tested in trial NCT02932410?
The interventions under investigation include: Macitentan (DRUG), Standard-of-care (OTHER).
Who is sponsoring clinical trial NCT02932410?
This trial is sponsored by Actelion, which has 63 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02932410's enrollment target sits among peer trials
165 1465th of 2000 higher than 531 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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