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NCT02922777 · ClinicalTrials.gov registry record · Phase 1

Trial of Dose Escalated BGB324 in Previously Treated Non-small Cell Lung Cancer.

A Phase 1 study, sponsored by University of Texas Southwestern Medical Center.

Completed
Registry status
Phase 1
Development phase
23
Enrollment target

NCT02922777: Completed Phase 1 study, sponsored by University of Texas Southwestern Medical Center.

NCT02922777 is a Phase 1 study that has completed, run by University of Texas Southwestern Medical Center. The registered enrollment target is 23 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (62% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02922777, a Phase 1 study, has completed, sponsored by University of Texas Southwestern Medical Center.

COMPLETED
Registry status
Phase 1
Development phase
23 participants
Enrollment target

Study Summary

This study is being done to evaluate the safety of the investigational study drug, BGB324 when administered in combination with docetaxel, and to establish the maximum tolerated dose.

Primary Outcome

Determine and recommended the Phase 2 dose of BGB324 administered with the standard dose of docetaxel in patients in NSCLC by pharmacodynamics and pharmacokinetic assessments.

Interventions

  • DRUG Docetaxel
  • DRUG BGB324

Trial Details

FieldValue
Enrollment Target 23 participants
Start Date 2016-11
Est. Completion 2023-04-04
Phase Phase 1

What the finished NCT02922777 record still lists

NCT02922777 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 23 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (62% lower).

The record links to 0 conditions, and to 2 interventions - of which Docetaxel is the first listed.

NCT02922777 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02922777 about?

NCT02922777 is a clinical study titled "Trial of Dose Escalated BGB324 in Previously Treated Non-small Cell Lung Cancer.". This study is being done to evaluate the safety of the investigational study drug, BGB324 when administered in combination with docetaxel, and to establish the maximum tolerated dose.

What is the current status of trial NCT02922777?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 23 participants. The study started on 2016-11. Estimated completion is 2023-04-04.

What interventions are being tested in trial NCT02922777?

The interventions under investigation include: Docetaxel (DRUG), BGB324 (DRUG).

Who is sponsoring clinical trial NCT02922777?

This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02922777's enrollment target sits among peer trials

23 1596th of 2000 higher than 400 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02922777, the US trial registry maintained by the National Library of Medicine. NCT02922777 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.