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NCT02918552 · ClinicalTrials.gov registry record · Phase 2
Oral Nitrite for Older Heart Failure With Preserved Ejection Fraction
A Phase 2 study, sponsored by Gladwin, Mark, MD.
- Completed
- Registry status
- Phase 2
- Development phase
- 15
- Enrollment target
NCT02918552: Completed Phase 2 study, sponsored by Gladwin, Mark, MD.
NCT02918552 is a Phase 2 study that has completed, run by Gladwin, Mark, MD. The registered enrollment target is 15 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (89% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02918552, a Phase 2 study, has completed, sponsored by Gladwin, Mark, MD.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 15 participants
- Enrollment target
Study Summary
This is a randomized double blinded controlled trial of 20-40 mg sodium nitrite tid in subjects with HFpEF. Primary outcomes are measures of physical function with non-invasive and invasive cardiopulmonary exercise testing, and fatigability, skeletal muscle bioenergetics, serology including inflammatory markers and platelet bioenergetics, quality of life measures.
Primary Outcome
Assessment of peak Oxygen uptake (VO2) maximum via symptom limited exercise testing
Interventions
- DRUG Control
- DRUG sodium nitrite
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2017-04-03 |
| Est. Completion | 2018-12-31 |
| Phase | Phase 2 |
What the finished NCT02918552 record still lists
NCT02918552 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (89% lower).
The record links to 0 conditions, and to 2 interventions - of which Control is the first listed.
NCT02918552 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02918552 about?
NCT02918552 is a clinical study titled "Oral Nitrite for Older Heart Failure With Preserved Ejection Fraction". This is a randomized double blinded controlled trial of 20-40 mg sodium nitrite tid in subjects with HFpEF. Primary outcomes are measures of physical function with non-invasive and invasive cardiopulmonary exercise testing, and fatigability, skeletal muscle bioenergetics, serology including inflamma...
What is the current status of trial NCT02918552?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 15 participants. The study started on 2017-04-03. Estimated completion is 2018-12-31.
What interventions are being tested in trial NCT02918552?
The interventions under investigation include: Control (DRUG), sodium nitrite (DRUG).
Who is sponsoring clinical trial NCT02918552?
This trial is sponsored by Gladwin, Mark, MD, which has 11 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02918552's enrollment target sits among peer trials
15 1919th of 2000 higher than 60 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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