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NCT02916810 · ClinicalTrials.gov registry record · NA
Alternative Stimulation Mode and Location for Auditory Hallucination Neuromodulation Treatment
A NA study of Schizophrenia and Related Disorders, sponsored by The University of Texas Health Science Center, Houston.
- Recruiting
- Registry status
- NA
- Development phase
- 140
- Enrollment target
- 1
- Study location
NCT02916810: Recruiting NA study of Schizophrenia and Related Disorders, sponsored by The University of Texas Health Science Center, Houston.
NCT02916810 is a NA study of Schizophrenia and Related Disorders that is actively recruiting participants, run by The University of Texas Health Science Center, Houston. The registered enrollment target is 140 participants, below the 246-participant average among 4 other Schizophrenia and Related Disorders trials with a reported enrollment target (43% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02916810, a NA study of Schizophrenia and Related Disorders, is actively recruiting participants, sponsored by The University of Texas Health Science Center, Houston.
- RECRUITING
- Registry status
- NA
- Development phase
- 140 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of the study is to test the hypothesis that functionally navigated repetitive TMS stimulations to the prefrontal cortex (PFC) modulate aberrant cortical electrical activities at PFC circuitry. The TMS location of the PFC site will be individually localized by the symptom-related functional connectivity between PFC and symptom related areas (such as the auditory and language processing cortex). The investigators predict that such modulation will correct abnormal activities in patients with schizophrenia, reduce symptoms, especially auditory hallucination, and improve working memory/sustained attention performance.
Primary Outcome
Functional magnetic resonance imaging (fMRI) is used to evaluate the brain activities that are corresponding to the treatment effect on auditory hallucination.
Conditions Studied
Interventions
- DEVICE Active rTMS stimulation
- DEVICE Sham rTMS stimulation
Study Locations (1)
Texas
- The University of Texas Health Science Center at Houston - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 140 participants |
| Start Date | 2025-02-01 |
| Est. Completion | 2029-07-01 |
| Phase | NA |
What NCT02916810 shows while recruiting
NCT02916810 is an interventional study that assigns participants to a tested intervention. The registered 140 participants enrollment target is mid-sized for trials with a published cap, below the 246-participant average among 4 other Schizophrenia and Related Disorders trials with a reported enrollment target (43% lower).
The record links to 1 condition, with Schizophrenia and Related Disorders appearing as the primary indexed condition, and to 2 interventions - of which Active rTMS stimulation is the first listed.
NCT02916810 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT02916810 about?
NCT02916810 is a clinical study titled "Alternative Stimulation Mode and Location for Auditory Hallucination Neuromodulation Treatment". The purpose of the study is to test the hypothesis that functionally navigated repetitive TMS stimulations to the prefrontal cortex (PFC) modulate aberrant cortical electrical activities at PFC circuitry. The TMS location of the PFC site will be individually localized by the symptom-related function...
What is the current status of trial NCT02916810?
This trial is currently recruiting. It is a NA study. The enrollment target is 140 participants. The study started on 2025-02-01. Estimated completion is 2029-07-01.
What conditions does trial NCT02916810 study?
This clinical trial studies the following conditions: Schizophrenia and Related Disorders.
What interventions are being tested in trial NCT02916810?
The interventions under investigation include: Active rTMS stimulation (DEVICE), Sham rTMS stimulation (DEVICE).
Who is sponsoring clinical trial NCT02916810?
This trial is sponsored by The University of Texas Health Science Center, Houston, which has 732 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02916810 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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