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NCT02911792 · ClinicalTrials.gov registry record · Phase 4

Effect of Farxiga on Renal Function and Size in Type 2 Diabetic Patients With Hyperfiltration

A Phase 4 study, sponsored by The University of Texas Health Science Center at San Antonio.

Completed
Registry status
Phase 4
Development phase
72
Enrollment target

NCT02911792: Completed Phase 4 study, sponsored by The University of Texas Health Science Center at San Antonio.

NCT02911792 is a Phase 4 study that has completed, run by The University of Texas Health Science Center at San Antonio. The registered enrollment target is 72 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (86% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02911792, a Phase 4 study, has completed, sponsored by The University of Texas Health Science Center at San Antonio.

COMPLETED
Registry status
Phase 4
Development phase
72 participants
Enrollment target

Study Summary

The investigators propose to treat newly diagnosed, hyperfiltering T2DM patients with or without microalbuminuria with dapagliflozin or metformin for 4 months. The metformin-treated group will serve as controls for improved glycemic control, since the investigators have shown that insulin therapy to normalize A1c reduces hyperfiltration and kidney size in T1DM patients.

Primary Outcome

Change from baseline in GFR after treatment from baseline to 4 months

Interventions

  • DRUG Metformin
  • DRUG Dapagliflozin
  • DRUG Glipizide 5 MG

Trial Details

FieldValue
Enrollment Target 72 participants
Start Date 2016-12-20
Est. Completion 2023-07-11
Phase Phase 4

What the finished NCT02911792 record still lists

NCT02911792 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 72 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (86% lower).

The record links to 0 conditions, and to 3 interventions - of which Metformin is the first listed.

NCT02911792 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02911792 about?

NCT02911792 is a clinical study titled "Effect of Farxiga on Renal Function and Size in Type 2 Diabetic Patients With Hyperfiltration". The investigators propose to treat newly diagnosed, hyperfiltering T2DM patients with or without microalbuminuria with dapagliflozin or metformin for 4 months. The metformin-treated group will serve as controls for improved glycemic control, since the investigators have shown that insulin therapy to...

What is the current status of trial NCT02911792?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 72 participants. The study started on 2016-12-20. Estimated completion is 2023-07-11.

What interventions are being tested in trial NCT02911792?

The interventions under investigation include: Metformin (DRUG), Dapagliflozin (DRUG), Glipizide 5 MG (DRUG).

Who is sponsoring clinical trial NCT02911792?

This trial is sponsored by The University of Texas Health Science Center at San Antonio, which has 378 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02911792's enrollment target sits among peer trials

72 1035th of 2000 higher than 961 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02911792, the US trial registry maintained by the National Library of Medicine. NCT02911792 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.