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NCT02905110 · ClinicalTrials.gov registry record · Early Phase 1

Methotrexate and Etoposide Infusions Into the Fourth Ventricle in Children with Recurrent Posterior Fossa Brain Tumors

A Early Phase 1 study, sponsored by The University of Texas Health Science Center, Houston.

Completed
Registry status
Early Phase 1
Development phase
3
Enrollment target

NCT02905110 is a Early Phase 1 study that has completed, run by The University of Texas Health Science Center, Houston. The registered enrollment target is 3 participants.

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The verdict

NCT02905110, a Early Phase 1 study, has completed, sponsored by The University of Texas Health Science Center, Houston.

COMPLETED
Registry status
Early Phase 1
Development phase
3 participants
Enrollment target

Study Summary

The goal of this clinical research study is to establish the safety of simultaneous infusions of methotrexate and etoposide into the fourth ventricle of the brain or resection cavity in patients with recurrent malignant posterior fossa brain tumors. These tumors include medulloblastoma, ependymoma, atypical teratoid/rhabdoid tumor or other malignant brain tumor with recurrence or progression involving anywhere in the brain and/or spine. Patients' disease must have originated in the posterior fossa of the brain.

Interventions

  • DRUG Etoposide
  • DRUG Methotrexate
  • PROCEDURE Ommaya Reservoir

Trial Details

FieldValue
Enrollment Target 3 participants
Start Date 2017-10-12
Est. Completion 2022-03-04
Phase Early Phase 1

What the Registry Record Tells You About NCT02905110

The ClinicalTrials.gov registry entry for NCT02905110 describes a study currently listed as completed, categorized as Early Phase 1. The registered enrollment target is 3 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is The University of Texas Health Science Center, Houston, which has 732 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Etoposide is the first listed.

NCT02905110 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02905110 about?

NCT02905110 is a clinical study titled "Methotrexate and Etoposide Infusions Into the Fourth Ventricle in Children with Recurrent Posterior Fossa Brain Tumors". The goal of this clinical research study is to establish the safety of simultaneous infusions of methotrexate and etoposide into the fourth ventricle of the brain or resection cavity in patients with recurrent malignant posterior fossa brain tumors. These tumors include medulloblastoma, ependymoma, ...

What is the current status of trial NCT02905110?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 3 participants. The study started on 2017-10-12. Estimated completion is 2022-03-04.

What interventions are being tested in trial NCT02905110?

The interventions under investigation include: Etoposide (DRUG), Methotrexate (DRUG), Ommaya Reservoir (PROCEDURE).

Who is sponsoring clinical trial NCT02905110?

This trial is sponsored by The University of Texas Health Science Center, Houston, which has 732 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.