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NCT02898103 · ClinicalTrials.gov registry record · NA
Percutaneous Peripheral Nerve Stimulation (Neuromodulation) for Postoperative Analgesia
A NA study, sponsored by University of California, San Diego.
- Completed
- Registry status
- NA
- Development phase
- 7
- Enrollment target
NCT02898103: Completed NA study, sponsored by University of California, San Diego.
NCT02898103 is a NA study that has completed, run by University of California, San Diego. The registered enrollment target is 7 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02898103, a NA study, has completed, sponsored by University of California, San Diego.
- COMPLETED
- Registry status
- NA
- Development phase
- 7 participants
- Enrollment target
Study Summary
The moderate-to-severe pain many patients experience following orthopedic surgery is often treated with opioids, which are associated with side effects such as nausea/vomiting, sedation, and respiratory depression (and a risk of abuse). Potent site-specific analgesia with fewer side effects may be provided with a "continuous peripheral nerve block," which involves the percutaneous insertion of a catheter adjacent to the peripheral nerve(s) supplying a surgical site. Local anesthetic is introduced via the catheter. However, there are major problems with continuous nerve blocks that have dramatically limited their use outside academic centers. Percutaneous peripheral nerve stimulation (PNS) or "nerve modulation" is an alternative method of pain control involving the insertion of an electrical lead through an introducing needle-obviating an open surgical incision for placement-followed by the introduction of electric current to produce analgesia. This modality has been used to treat chronic pain, but it has not been evaluated with a randomized, controlled study when applied to acute pain management (post-surgical analgesia). This temporary therapy has multiple theoretical benefits over existing analgesics, such as a lack of systemic side effects (e.g., nausea, respiratory depression), an absence of induced muscle weakness, and a reduced risk of adverse events (e.g. infection). The purpose of the proposed randomized, double-masked, placebo-controlled, crossover, feasibility study is to explore the possibility of treating postoperative pain with ultrasound-guided percutaneous PNS and, if so, to help power a subsequent definitive randomized, controlled trial.
Primary Outcome
Pain is evaluated on a Numeric Rating Scale: 0-10 scale with 0=no pain and 10=worst imaginable pain. The outcome measure is calculated as such: the pain score 5 and then 10 minutes after the stimulator is first activated on the Numeric Rating Scale divided by the baseline pain score measured on the same scale. Of note, although this is a crossover design, the order of treatment does influence the effects of each treatment, so the 7 total subjects cannot be grouped together for the active portion
Interventions
- DEVICE Sham stimulation
- DEVICE Percutaneous peripheral nerve stimulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7 participants |
| Start Date | 2017-02-24 |
| Est. Completion | 2018-09-20 |
| Phase | NA |
What the finished NCT02898103 record still lists
NCT02898103 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 7 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 2 interventions - of which Sham stimulation is the first listed.
NCT02898103 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02898103 about?
NCT02898103 is a clinical study titled "Percutaneous Peripheral Nerve Stimulation (Neuromodulation) for Postoperative Analgesia". The moderate-to-severe pain many patients experience following orthopedic surgery is often treated with opioids, which are associated with side effects such as nausea/vomiting, sedation, and respiratory depression (and a risk of abuse). Potent site-specific analgesia with fewer side effects may be p...
What is the current status of trial NCT02898103?
This trial is currently completed. It is a NA study. The enrollment target is 7 participants. The study started on 2017-02-24. Estimated completion is 2018-09-20.
What interventions are being tested in trial NCT02898103?
The interventions under investigation include: Sham stimulation (DEVICE), Percutaneous peripheral nerve stimulation (DEVICE).
Who is sponsoring clinical trial NCT02898103?
This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02898103's enrollment target sits among peer trials
7 1982nd of 2000 higher than 18 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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