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NCT02893930 · ClinicalTrials.gov registry record · Phase 2

Sapanisertib in Treating Patients With Metastatic or Refractory Pancreatic Neuroendocrine Tumor That Cannot Be Removed by Surgery

A Phase 2 study, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 2
Development phase
13
Enrollment target

NCT02893930: Completed Phase 2 study, sponsored by National Cancer Institute (NCI).

NCT02893930 is a Phase 2 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 13 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02893930, a Phase 2 study, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 2
Development phase
13 participants
Enrollment target

Study Summary

This phase II trial studies how well sapanisertib works in treating patients with pancreatic neuroendocrine tumor that has spread to other places in the body (metastatic), does not respond to treatment (refractory), or cannot be surgically removed. Drugs such as sapanisertib may stop the growth or shrink tumor cells by blocking some of the enzymes needed for cell growth.

Primary Outcome

Response includes complete response (CR) and partial response (PR). CR is defined as disappearance of all lesions. Any pathological lymph nodes (whether target or non-target) must have reduction in short axis to \< 10 mm. PR is defined as at least a 30% decrease in the sum of the diameters of target lesions, taking as reference the baseline sum diameters.

Interventions

  • DRUG Sapanisertib

Trial Details

FieldValue
Enrollment Target 13 participants
Start Date 2017-04-28
Est. Completion 2022-12-21
Phase Phase 2
National Cancer Institute (NCI)

3,257 total trials

What the finished NCT02893930 record still lists

NCT02893930 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 13 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (90% lower).

The record links to 0 conditions, and to 1 intervention - of which Sapanisertib is the first listed.

NCT02893930 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02893930 about?

NCT02893930 is a clinical study titled "Sapanisertib in Treating Patients With Metastatic or Refractory Pancreatic Neuroendocrine Tumor That Cannot Be Removed by Surgery". This phase II trial studies how well sapanisertib works in treating patients with pancreatic neuroendocrine tumor that has spread to other places in the body (metastatic), does not respond to treatment (refractory), or cannot be surgically removed. Drugs such as sapanisertib may stop the growth or s...

What is the current status of trial NCT02893930?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 13 participants. The study started on 2017-04-28. Estimated completion is 2022-12-21.

What interventions are being tested in trial NCT02893930?

The interventions under investigation include: Sapanisertib (DRUG).

Who is sponsoring clinical trial NCT02893930?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02893930's enrollment target sits among peer trials

13 1947th of 2000 higher than 53 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02893930, the US trial registry maintained by the National Library of Medicine. NCT02893930 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.