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NCT02892734 · ClinicalTrials.gov registry record · Phase 2

Ipilimumab and Nivolumab in Treating Patients With Recurrent Stage IV HER2 Negative Inflammatory Breast Cancer

A Phase 2 study, sponsored by Northwestern University.

Terminated
Registry status
Phase 2
Development phase
3
Enrollment target

NCT02892734 is a Phase 2 study that was terminated before completion, run by Northwestern University. The registered enrollment target is 3 participants.

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The verdict

NCT02892734, a Phase 2 study, was terminated before completion, sponsored by Northwestern University.

TERMINATED
Registry status
Phase 2
Development phase
3 participants
Enrollment target

Study Summary

The purpose of this research study is to look at the efficacy (the effect on tumor) and the safety (the effect on body) of the study drugs when given as a combination in patients with metastatic recurrent epidermal growth factor receptor 2 (HER2) negative inflammatory breast cancer. This is a phase II study of 2 drugs used in combination: nivolumab and ipilimumab. The combination of these drugs is already approved by the Food and Drug Administration (FDA) to treat advanced melanoma (a type of skin cancer). Nivolumab and ipilimumab are not approved by the FDA for patients with metastatic recurrent HER2 negative inflammatory breast cancer, hence the treatment is considered experimental or investigational.

Interventions

  • OTHER Laboratory Biomarker Analysis
  • BIOLOGICAL Nivolumab
  • BIOLOGICAL Ipilimumab

Trial Details

FieldValue
Enrollment Target 3 participants
Start Date 2017-09-18
Est. Completion 2019-02-04
Phase Phase 2

Sponsor

Northwestern University

1,209 total trials

What the Registry Record Tells You About NCT02892734

The ClinicalTrials.gov registry entry for NCT02892734 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 3 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Northwestern University, which has 1,209 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Laboratory Biomarker Analysis is the first listed.

NCT02892734 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02892734 about?

NCT02892734 is a clinical study titled "Ipilimumab and Nivolumab in Treating Patients With Recurrent Stage IV HER2 Negative Inflammatory Breast Cancer". The purpose of this research study is to look at the efficacy (the effect on tumor) and the safety (the effect on body) of the study drugs when given as a combination in patients with metastatic recurrent epidermal growth factor receptor 2 (HER2) negative inflammatory breast cancer. This is a phase ...

What is the current status of trial NCT02892734?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 3 participants. The study started on 2017-09-18. Estimated completion is 2019-02-04.

What interventions are being tested in trial NCT02892734?

The interventions under investigation include: Laboratory Biomarker Analysis (OTHER), Nivolumab (BIOLOGICAL), Ipilimumab (BIOLOGICAL).

Who is sponsoring clinical trial NCT02892734?

This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.