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NCT02889133 · ClinicalTrials.gov registry record · NA

Donor Iron Deficiency Study - Red Blood Cells From Iron-deficient Donors: Recovery and Storage Quality

A NA study, sponsored by Columbia University.

Completed
Registry status
NA
Development phase
79
Enrollment target

NCT02889133: Completed NA study, sponsored by Columbia University.

NCT02889133 is a NA study that has completed, run by Columbia University. The registered enrollment target is 79 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02889133, a NA study, has completed, sponsored by Columbia University.

COMPLETED
Registry status
NA
Development phase
79 participants
Enrollment target

Study Summary

Primary Hypothesis * The 24-hour post-transfusion RBC recovery of units obtained from donors exhibiting iron-deficient erythropoiesis will not meet FDA standards for clinical use. * The 24-hour post-transfusion RBC recovery of units obtained after intravenous iron repletion will improve significantly and will meet FDA standards for clinical use.

Primary Outcome

Comparison of the percentage change in 51-Chromium-labeled RBCs remaining from pre- and 24 hour post-transfusion measurement between the Iron Repletion and the Placebo group. The post-transfusion recovery represents the percent of 51-Chromium-labeled RBCs remaining in circulation 24 hours after infusion as compared to an extrapolated time zero measurement.

Interventions

  • DRUG Saline
  • PROCEDURE Blood Donation
  • DRUG Iron-dextran
  • PROCEDURE 24-hour PTR

Trial Details

FieldValue
Enrollment Target 79 participants
Start Date 2017-01
Est. Completion 2021-10-05
Phase NA
Columbia University

958 total trials

What the finished NCT02889133 record still lists

NCT02889133 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 79 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower).

The record links to 0 conditions, and to 4 interventions - of which Saline is the first listed.

NCT02889133 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02889133 about?

NCT02889133 is a clinical study titled "Donor Iron Deficiency Study - Red Blood Cells From Iron-deficient Donors: Recovery and Storage Quality". Primary Hypothesis * The 24-hour post-transfusion RBC recovery of units obtained from donors exhibiting iron-deficient erythropoiesis will not meet FDA standards for clinical use. * The 24-hour post-transfusion RBC recovery of units obtained after intravenous iron repletion will improve significant...

What is the current status of trial NCT02889133?

This trial is currently completed. It is a NA study. The enrollment target is 79 participants. The study started on 2017-01. Estimated completion is 2021-10-05.

What interventions are being tested in trial NCT02889133?

The interventions under investigation include: Saline (DRUG), Blood Donation (PROCEDURE), Iron-dextran (DRUG), 24-hour PTR (PROCEDURE).

Who is sponsoring clinical trial NCT02889133?

This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02889133's enrollment target sits among peer trials

79 1060th of 2000 higher than 941 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02889133, the US trial registry maintained by the National Library of Medicine. NCT02889133 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.