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NCT02888119 · ClinicalTrials.gov registry record · NA
Imaging Biomarkers of Knee Osteoarthritis
A NA study of Osteoarthritis, sponsored by NYU Langone Health.
- Completed
- Registry status
- NA
- Development phase
- 50
- Enrollment target
- 1
- Study location
NCT02888119: Completed NA study of Osteoarthritis, sponsored by NYU Langone Health.
NCT02888119 is a NA study of Osteoarthritis that has completed, run by NYU Langone Health. The registered enrollment target is 50 participants, below the 817-participant average among 135 other Osteoarthritis trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02888119, a NA study of Osteoarthritis, has completed, sponsored by NYU Langone Health.
- COMPLETED
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
This study aims to develop, evaluate and translate highly accelerated imaging sequences (each protocol under 5 minutes) for in-vivo knee Osteoarthritis applications on a standard clinical 3T scanner using novel compression sensing and parallel imaging strategies.The overarching objective of the study is to establish a non-invasive imaging biomarker based on the development of rapid relaxation mapping with compressed sensing (CS) that will be clinically useful for assessment of early Osteoarthritis. A total of 90 subjects including 30 patients with high risk of developing knee osteoarthritis (OA), 30 patients with mild OA and 30 healthy controls will be accrued.
Primary Outcome
MRI exam of accelerated 3D-T1p conducted on whole knee joint specimens to determine cartilage composition, measured as T1ρ relaxation time. T1ρ MRI relaxation times refer to the proteoglycan density within cartilage. Images taken at baseline and at Month 24.
Conditions Studied
Interventions
- DEVICE PRISMA 3T MRI scanner (Siemens Medical Solutions)
Study Locations (1)
New York
- New York University School of Medicine - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2016-07 |
| Est. Completion | 2021-12-13 |
| Phase | NA |
What the finished NCT02888119 record still lists
NCT02888119 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 817-participant average among 135 other Osteoarthritis trials with a reported enrollment target (94% lower).
The record links to 1 condition, with Osteoarthritis appearing as the primary indexed condition, and to 1 intervention - of which PRISMA 3T MRI scanner (Siemens Medical Solutions) is the first listed.
NCT02888119 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT02888119 about?
NCT02888119 is a clinical study titled "Imaging Biomarkers of Knee Osteoarthritis". This study aims to develop, evaluate and translate highly accelerated imaging sequences (each protocol under 5 minutes) for in-vivo knee Osteoarthritis applications on a standard clinical 3T scanner using novel compression sensing and parallel imaging strategies.The overarching objective of the stud...
What is the current status of trial NCT02888119?
This trial is currently completed. It is a NA study. The enrollment target is 50 participants. The study started on 2016-07. Estimated completion is 2021-12-13.
What conditions does trial NCT02888119 study?
This clinical trial studies the following conditions: Osteoarthritis.
What interventions are being tested in trial NCT02888119?
The interventions under investigation include: PRISMA 3T MRI scanner (Siemens Medical Solutions) (DEVICE).
Who is sponsoring clinical trial NCT02888119?
This trial is sponsored by NYU Langone Health, which has 1,164 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02888119 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02888119's enrollment target sits among peer trials
50 115th of 135 higher than 18 of 135 other Osteoarthritis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Osteoarthritis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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