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NCT02881775 · ClinicalTrials.gov registry record · NA
Immediate Effects of rTMS on Excitability of the Quadriceps With Knee Osteoarthritis
A NA study, sponsored by University of North Carolina, Chapel Hill.
- Completed
- Registry status
- NA
- Development phase
- 20
- Enrollment target
NCT02881775: Completed NA study, sponsored by University of North Carolina, Chapel Hill.
NCT02881775 is a NA study that has completed, run by University of North Carolina, Chapel Hill. The registered enrollment target is 20 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02881775, a NA study, has completed, sponsored by University of North Carolina, Chapel Hill.
- COMPLETED
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
Study Summary
The purpose of the study is to identify things that influence the ability to "turn on" the thigh muscle (quadriceps). The thigh muscle tends to be under active with knee osteoarthritis, which may make it difficult to strengthen the muscle. The investigators are also testing a new technology called repetitive transcranial magnetic stimulation (rTMS) to determine whether it may help "turn up" activity in the under active thigh muscle immediately after its application. rTMS uses a targeted pulsed magnetic field, similar to what is used in an MRI (magnetic resonance imaging) machine to send an electrical signal from the brain to the thigh muscle.
Primary Outcome
Quadriceps Central Activation Ratio (CAR) is a percentage of the amount of torque produced during the superimposed burst technique using maximal voluntary isometric contraction (MVIC) and superimposed burst torque. It is reported on a scale of 0 (worst) to 100% (best) activation.
Interventions
- DEVICE rTMS and exercise
- DEVICE Sham rTMS and exercise
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2016-09 |
| Est. Completion | 2018-06-26 |
| Phase | NA |
What the finished NCT02881775 record still lists
NCT02881775 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which rTMS and exercise is the first listed.
NCT02881775 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02881775 about?
NCT02881775 is a clinical study titled "Immediate Effects of rTMS on Excitability of the Quadriceps With Knee Osteoarthritis". The purpose of the study is to identify things that influence the ability to "turn on" the thigh muscle (quadriceps). The thigh muscle tends to be under active with knee osteoarthritis, which may make it difficult to strengthen the muscle. The investigators are also testing a new technology called r...
What is the current status of trial NCT02881775?
This trial is currently completed. It is a NA study. The enrollment target is 20 participants. The study started on 2016-09. Estimated completion is 2018-06-26.
What interventions are being tested in trial NCT02881775?
The interventions under investigation include: rTMS and exercise (DEVICE), Sham rTMS and exercise (DEVICE).
Who is sponsoring clinical trial NCT02881775?
This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02881775's enrollment target sits among peer trials
20 1768th of 2000 higher than 140 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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