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NCT02877381 · ClinicalTrials.gov registry record · Phase 4
Tranexamic Acid in Revision Total Joint Arthroplasty
A Phase 4 study, sponsored by Rush University Medical Center.
- Completed
- Registry status
- Phase 4
- Development phase
- 175
- Enrollment target
NCT02877381: Completed Phase 4 study, sponsored by Rush University Medical Center.
NCT02877381 is a Phase 4 study that has completed, run by Rush University Medical Center. The registered enrollment target is 175 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (66% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02877381, a Phase 4 study, has completed, sponsored by Rush University Medical Center.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 175 participants
- Enrollment target
Study Summary
To determine the optimal dosing regimen and route of administration of tranexamic acid (TXA) \[single dose intravenous (IV), double dose intravenous, intravenous + topical, and oral repeated dosing\] to minimize post-operative blood loss and transfusion requirements following revision total knee arthroplasty (RTKA).
Primary Outcome
Pre-operative hemoglobin minus the lowest post-operative hemoglobin prior to any transfusion
Interventions
- PROCEDURE Revision Total Knee Arthroplasty (TKA)
- PROCEDURE Revision Total Hip Arthroplasty (THA)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 175 participants |
| Start Date | 2016-04 |
| Est. Completion | 2019-08-01 |
| Phase | Phase 4 |
What the finished NCT02877381 record still lists
NCT02877381 is an interventional study that assigns participants to a tested intervention. The registered 175 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (66% lower).
The record links to 0 conditions, and to 2 interventions - of which Revision Total Knee Arthroplasty (TKA) is the first listed.
NCT02877381 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02877381 about?
NCT02877381 is a clinical study titled "Tranexamic Acid in Revision Total Joint Arthroplasty". To determine the optimal dosing regimen and route of administration of tranexamic acid (TXA) \[single dose intravenous (IV), double dose intravenous, intravenous + topical, and oral repeated dosing\] to minimize post-operative blood loss and transfusion requirements following revision total knee art...
What is the current status of trial NCT02877381?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 175 participants. The study started on 2016-04. Estimated completion is 2019-08-01.
What interventions are being tested in trial NCT02877381?
The interventions under investigation include: Revision Total Knee Arthroplasty (TKA) (PROCEDURE), Revision Total Hip Arthroplasty (THA) (PROCEDURE).
Who is sponsoring clinical trial NCT02877381?
This trial is sponsored by Rush University Medical Center, which has 320 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02877381's enrollment target sits among peer trials
175 478th of 2000 higher than 1,521 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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