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NCT02866435 · ClinicalTrials.gov registry record · Early Phase 1
Identifying the Brain Substrates of Hypoglycemia Unawareness in Type 1 Diabetes
A Early Phase 1 study, sponsored by University of Minnesota.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 27
- Enrollment target
NCT02866435: Completed Early Phase 1 study, sponsored by University of Minnesota.
NCT02866435 is a Early Phase 1 study that has completed, run by University of Minnesota. The registered enrollment target is 27 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (49% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02866435, a Early Phase 1 study, has completed, sponsored by University of Minnesota.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 27 participants
- Enrollment target
Study Summary
The purpose of this study is to investigate how the brain responds to low blood glucose in non-diabetic individuals. The ultimate goal is to understand the brain substrates of hypoglycemia unawareness, a condition that can occur in patients with type1 diabetes undergoing insulin treatment.In the present study, the investigators focus on differences between two groups of non-diabetic subjects: one group who experienced two episodes of hypoglycemia the day prior to the study (and supposedly developed some level of unawareness to hypoglycemia), and one group who did not. In this study, a 3 tesla MRI scanner is used to acquire brain images. The imaging system is identical to the ones used in hospitals.
Primary Outcome
Functional connectivity will be measured with MRI at 3 Tesla
Interventions
- DRUG Insulin
- DRUG Glucose
- DRUG Potassium phosphate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 27 participants |
| Start Date | 2016-11 |
| Est. Completion | 2019-12-30 |
| Phase | Early Phase 1 |
What the finished NCT02866435 record still lists
NCT02866435 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 27 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (49% lower).
The record links to 0 conditions, and to 3 interventions - of which Insulin is the first listed.
NCT02866435 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02866435 about?
NCT02866435 is a clinical study titled "Identifying the Brain Substrates of Hypoglycemia Unawareness in Type 1 Diabetes". The purpose of this study is to investigate how the brain responds to low blood glucose in non-diabetic individuals. The ultimate goal is to understand the brain substrates of hypoglycemia unawareness, a condition that can occur in patients with type1 diabetes undergoing insulin treatment.In the pre...
What is the current status of trial NCT02866435?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 27 participants. The study started on 2016-11. Estimated completion is 2019-12-30.
What interventions are being tested in trial NCT02866435?
The interventions under investigation include: Insulin (DRUG), Glucose (DRUG), Potassium phosphate (DRUG).
Who is sponsoring clinical trial NCT02866435?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02866435's enrollment target sits among peer trials
27 963rd of 2000 higher than 1,025 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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