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NCT02857426 · ClinicalTrials.gov registry record · Phase 2

A Study of Nivolumab in Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL) and Relapsed/Refractory Primary Testicular Lymphoma (PTL)

A Phase 2 study, sponsored by Bristol-Myers Squibb.

Completed
Registry status
Phase 2
Development phase
66
Enrollment target

NCT02857426: Completed Phase 2 study, sponsored by Bristol-Myers Squibb.

NCT02857426 is a Phase 2 study that has completed, run by Bristol-Myers Squibb. The registered enrollment target is 66 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (50% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02857426, a Phase 2 study, has completed, sponsored by Bristol-Myers Squibb.

COMPLETED
Registry status
Phase 2
Development phase
66 participants
Enrollment target

Study Summary

The purpose of this study is to determine whether Nivolumab is effective in the treatment of Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL) and Relapsed/Refractory Primary Testicular Lymphoma (PTL)

Primary Outcome

Percentage of participants with a confirmed objective response rate (ORR) by blinded independent central review (BICR) assessment was analyzed and reported for both PCNSL and PTL patient populations. This endpoint is further defined as the percentage of participants with a best overall response (BOR) of complete response (CR) or partial response (PR), based on the IPCG Criteria for PCNSL and Lugano 2014 response evaluation for PTL, divided by the number of treated participants within each cohor

Interventions

  • DRUG Nivolumab

Trial Details

FieldValue
Enrollment Target 66 participants
Start Date 2016-10-21
Est. Completion 2020-11-24
Phase Phase 2
Bristol-Myers Squibb

1,025 total trials

What the finished NCT02857426 record still lists

NCT02857426 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 66 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (50% lower).

The record links to 0 conditions, and to 1 intervention - of which Nivolumab is the first listed.

NCT02857426 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02857426 about?

NCT02857426 is a clinical study titled "A Study of Nivolumab in Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL) and Relapsed/Refractory Primary Testicular Lymphoma (PTL)". The purpose of this study is to determine whether Nivolumab is effective in the treatment of Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL) and Relapsed/Refractory Primary Testicular Lymphoma (PTL)

What is the current status of trial NCT02857426?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 66 participants. The study started on 2016-10-21. Estimated completion is 2020-11-24.

What interventions are being tested in trial NCT02857426?

The interventions under investigation include: Nivolumab (DRUG).

Who is sponsoring clinical trial NCT02857426?

This trial is sponsored by Bristol-Myers Squibb, which has 1,025 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02857426's enrollment target sits among peer trials

66 975th of 2000 higher than 1,014 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02857426, the US trial registry maintained by the National Library of Medicine. NCT02857426 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.