Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT02854631 · ClinicalTrials.gov registry record · Phase 2

Selonsertib in Combination With Prednisolone Versus Prednisolone Alone in Participants With Severe Alcoholic Hepatitis (AH)

A Phase 2 study of Alcoholic Hepatitis (AH), sponsored by Gilead Sciences.

Completed
Registry status
Phase 2
Development phase
104
Enrollment target
20
Study locations

NCT02854631 is a Phase 2 study of Alcoholic Hepatitis (AH) that has completed, run by Gilead Sciences. The registered enrollment target is 104 participants. The trial reports 20 study locations across 12 states.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT02854631, a Phase 2 study of Alcoholic Hepatitis (AH), has completed, sponsored by Gilead Sciences.

COMPLETED
Registry status
Phase 2
Development phase
104 participants
Enrollment target
20
Study locations

Study Summary

The primary objective of this study is to evaluate the safety and tolerability of selonsertib (GS-4997) in combination with prednisolone versus prednisolone alone in participants with severe alcoholic hepatitis (AH).

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG Prednisolone
  • DRUG Selonsertib

Study Locations (20)

Other

  • Medizinische Universitat Graz - Graz
  • Universitätsklinik für Innere Medizin I - Innsbruck
  • Medical University Vienna - Vienna
  • Cliniques Universitaires UCL Saint-Luc - Brussels
  • CUB Hopital Erasme - Brussels
  • Ghent University Hospital - Ghent
  • Universitair Ziekenhuis Leuven - Leuven
  • Centre Hospitalier Universitaire de Liege - Liège

California

  • Southern California Research Centers - Coronado
  • Cedars Sinai Medical Center - Los Angeles

Arkansas

  • University of Arkansas for Medical Sciences - Little Rock

Florida

  • Cleveland Clinic Florida - Weston

Louisiana

  • Oschner Medical Center - New Orleans

Massachusetts

  • Beth Israel Deaconess Medical Center - Boston

Michigan

  • University of Michigan - Ann Arbor

Pennsylvania

  • University of Pennsylvania - Philadelphia

Trial Details

FieldValue
Enrollment Target 104 participants
Start Date 2016-09-01
Est. Completion 2018-05-31
Phase Phase 2

Sponsor

Gilead Sciences

504 total trials

What the Registry Record Tells You About NCT02854631

The ClinicalTrials.gov registry entry for NCT02854631 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 104 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Gilead Sciences, which has 504 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Alcoholic Hepatitis (AH) appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.

NCT02854631 reports 20 study locations spanning 12 distinct geographic areas - top geographies include Other, California, Arkansas.

Frequently Asked Questions

What is clinical trial NCT02854631 about?

NCT02854631 is a clinical study titled "Selonsertib in Combination With Prednisolone Versus Prednisolone Alone in Participants With Severe Alcoholic Hepatitis (AH)". The primary objective of this study is to evaluate the safety and tolerability of selonsertib (GS-4997) in combination with prednisolone versus prednisolone alone in participants with severe alcoholic hepatitis (AH).

What is the current status of trial NCT02854631?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 104 participants. The study started on 2016-09-01. Estimated completion is 2018-05-31.

What conditions does trial NCT02854631 study?

This clinical trial studies the following conditions: Alcoholic Hepatitis (AH).

What interventions are being tested in trial NCT02854631?

The interventions under investigation include: Placebo (DRUG), Prednisolone (DRUG), Selonsertib (DRUG).

Who is sponsoring clinical trial NCT02854631?

This trial is sponsored by Gilead Sciences, which has 504 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02854631 being conducted?

This trial has 20 study locations across Arkansas, California, Florida, Louisiana, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.