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NCT02852057 · ClinicalTrials.gov registry record · Phase 1
Effectiveness and Safety of Timolol and Dorzolamide Loaded Contact Lenses
A Phase 1 study, sponsored by University of Florida.
- Completed
- Registry status
- Phase 1
- Development phase
- 2
- Enrollment target
NCT02852057: Completed Phase 1 study, sponsored by University of Florida.
NCT02852057 is a Phase 1 study that has completed, run by University of Florida. The registered enrollment target is 2 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02852057, a Phase 1 study, has completed, sponsored by University of Florida.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 2 participants
- Enrollment target
Study Summary
This study focuses on glaucoma therapy by drug eluting contact lenses. The contact lens will be loaded with timolol maleate and dorzolamide hydrochloride, both of which are commonly used ophthalmic drugs. Additionally, the lenses will contain vitamin E ((+) α-tocopherol) as an additive for achieving extended release of the drugs. This study is to assess the safety of the drug loaded contact lenses and the effectiveness. Effectiveness will be a drop in IOP after using the lenses.
Primary Outcome
Pressure will be measured in trial subjects before placement of lenses and after day 1, day 2, day 4, day 7, and day 9
Interventions
- DRUG timolol maleate and dorzolamide hydrochloride
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2 participants |
| Start Date | 2018-01-18 |
| Est. Completion | 2021-08-10 |
| Phase | Phase 1 |
What the finished NCT02852057 record still lists
NCT02852057 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 2 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 1 intervention - of which timolol maleate and dorzolamide hydrochloride is the first listed.
NCT02852057 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02852057 about?
NCT02852057 is a clinical study titled "Effectiveness and Safety of Timolol and Dorzolamide Loaded Contact Lenses". This study focuses on glaucoma therapy by drug eluting contact lenses. The contact lens will be loaded with timolol maleate and dorzolamide hydrochloride, both of which are commonly used ophthalmic drugs. Additionally, the lenses will contain vitamin E ((+) α-tocopherol) as an additive for achieving...
What is the current status of trial NCT02852057?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 2 participants. The study started on 2018-01-18. Estimated completion is 2021-08-10.
What interventions are being tested in trial NCT02852057?
The interventions under investigation include: timolol maleate and dorzolamide hydrochloride (DRUG).
Who is sponsoring clinical trial NCT02852057?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02852057's enrollment target sits among peer trials
2 2000th of 2000 the lowest of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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