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NCT02844621 · ClinicalTrials.gov registry record · Early Phase 1
Effect of Proton Pump Inhibitors on Gut Microbiota and Systemic Inflammation in Older Adults
A Early Phase 1 study, sponsored by The University of Texas Health Science Center at San Antonio.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 25
- Enrollment target
NCT02844621: Completed Early Phase 1 study, sponsored by The University of Texas Health Science Center at San Antonio.
NCT02844621 is a Early Phase 1 study that has completed, run by The University of Texas Health Science Center at San Antonio. The registered enrollment target is 25 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (53% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02844621, a Early Phase 1 study, has completed, sponsored by The University of Texas Health Science Center at San Antonio.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 25 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate the effects of a common over-the-counter medication, omeprazole, on the normal gut bacteria and inflammation in the body in healthy older adults.
Primary Outcome
Bacterial taxa will be classified according to operational taxonomic units (OTUs). The change in the diversity of bacteria taxa will be compared between pre- and post-samples using the Bray-Curtis dissimilarity measure.
Interventions
- DRUG Omeprazole
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2016-05 |
| Est. Completion | 2016-12 |
| Phase | Early Phase 1 |
What the finished NCT02844621 record still lists
NCT02844621 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (53% lower).
The record links to 0 conditions, and to 1 intervention - of which Omeprazole is the first listed.
NCT02844621 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02844621 about?
NCT02844621 is a clinical study titled "Effect of Proton Pump Inhibitors on Gut Microbiota and Systemic Inflammation in Older Adults". The purpose of this study is to evaluate the effects of a common over-the-counter medication, omeprazole, on the normal gut bacteria and inflammation in the body in healthy older adults.
What is the current status of trial NCT02844621?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 25 participants. The study started on 2016-05. Estimated completion is 2016-12.
What interventions are being tested in trial NCT02844621?
The interventions under investigation include: Omeprazole (DRUG).
Who is sponsoring clinical trial NCT02844621?
This trial is sponsored by The University of Texas Health Science Center at San Antonio, which has 378 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02844621's enrollment target sits among peer trials
25 1000th of 2000 higher than 965 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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