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NCT02840799 · ClinicalTrials.gov registry record · Phase 2
Effect of KNO3 Compared to KCl on Oxygen UpTake in Heart Failure With Preserved Ejection Fraction (KNO3CK OUT HFPEF)
A Phase 2 study, sponsored by University of Pennsylvania.
- Completed
- Registry status
- Phase 2
- Development phase
- 84
- Enrollment target
NCT02840799: Completed Phase 2 study, sponsored by University of Pennsylvania.
NCT02840799 is a Phase 2 study that has completed, run by University of Pennsylvania. The registered enrollment target is 84 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (37% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02840799, a Phase 2 study, has completed, sponsored by University of Pennsylvania.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 84 participants
- Enrollment target
Study Summary
This trial seeks to assess if potassium nitrate (KNO3) therapy improves exercise capacity and oxygen uptake in heart failure patients with preserved ejection fraction (HFpEF).
Primary Outcome
Subjects will perform a maximal-effort peak oxygen consumption test using a supine bicycle exercise test with expired gas analysis.
Interventions
- DRUG Potassium Chloride (KCl)
- DRUG Potassium Nitrate (KNO3)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 84 participants |
| Start Date | 2016-08 |
| Est. Completion | 2022-08 |
| Phase | Phase 2 |
What the finished NCT02840799 record still lists
NCT02840799 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 84 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (37% lower).
The record links to 0 conditions, and to 2 interventions - of which Potassium Chloride (KCl) is the first listed.
NCT02840799 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02840799 about?
NCT02840799 is a clinical study titled "Effect of KNO3 Compared to KCl on Oxygen UpTake in Heart Failure With Preserved Ejection Fraction (KNO3CK OUT HFPEF)". This trial seeks to assess if potassium nitrate (KNO3) therapy improves exercise capacity and oxygen uptake in heart failure patients with preserved ejection fraction (HFpEF).
What is the current status of trial NCT02840799?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 84 participants. The study started on 2016-08. Estimated completion is 2022-08.
What interventions are being tested in trial NCT02840799?
The interventions under investigation include: Potassium Chloride (KCl) (DRUG), Potassium Nitrate (KNO3) (DRUG).
Who is sponsoring clinical trial NCT02840799?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02840799's enrollment target sits among peer trials
84 822nd of 2000 higher than 1,173 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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