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NCT02837432 · ClinicalTrials.gov registry record · Early Phase 1
The Effect of Cortisol Administration on Neural Correlates of Emotion in Depression
A Early Phase 1 study, sponsored by Stanford University.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 192
- Enrollment target
NCT02837432: Completed Early Phase 1 study, sponsored by Stanford University.
NCT02837432 is a Early Phase 1 study that has completed, run by Stanford University. The registered enrollment target is 192 participants, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (262% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02837432, a Early Phase 1 study, has completed, sponsored by Stanford University.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 192 participants
- Enrollment target
Study Summary
There is good evidence to suggest that the pathological version of sadness that people with Major Depression experience could be caused by the failure of the hormone cortisol to properly inhibit sadness-related brain activity in the subgenual cingulate cortex. This project investigates if the subgenual cingulate cortex has become insensitive to cortisol in patients with depression and tests for variants of the cortisol receptor genes that could predispose individuals to develop cortisol insensitivity.
Interventions
- DRUG Placebo
- DRUG Hydrocortisone acetate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 192 participants |
| Start Date | 2016-07 |
| Est. Completion | 2020-11-15 |
| Phase | Early Phase 1 |
What the finished NCT02837432 record still lists
NCT02837432 is an interventional study that assigns participants to a tested intervention. The registered 192 participants enrollment target is mid-sized for trials with a published cap, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (262% higher).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT02837432 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02837432 about?
NCT02837432 is a clinical study titled "The Effect of Cortisol Administration on Neural Correlates of Emotion in Depression". There is good evidence to suggest that the pathological version of sadness that people with Major Depression experience could be caused by the failure of the hormone cortisol to properly inhibit sadness-related brain activity in the subgenual cingulate cortex. This project investigates if the subgen...
What is the current status of trial NCT02837432?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 192 participants. The study started on 2016-07. Estimated completion is 2020-11-15.
What interventions are being tested in trial NCT02837432?
The interventions under investigation include: Placebo (DRUG), Hydrocortisone acetate (DRUG).
Who is sponsoring clinical trial NCT02837432?
This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02837432's enrollment target sits among peer trials
192 71st of 2000 higher than 1,930 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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