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NCT02823041 · ClinicalTrials.gov registry record · NA

Enhancing Cognitive Training Through Exercise Following a First Schizophrenia Episode

A NA study, sponsored by University of California, Los Angeles.

Completed
Registry status
NA
Development phase
100
Enrollment target

NCT02823041: Completed NA study, sponsored by University of California, Los Angeles.

NCT02823041 is a NA study that has completed, run by University of California, Los Angeles. The registered enrollment target is 100 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02823041, a NA study, has completed, sponsored by University of California, Los Angeles.

COMPLETED
Registry status
NA
Development phase
100 participants
Enrollment target

Study Summary

This is a confirmatory randomized controlled trial of the efficacy of a novel intervention combining neuroplasticity-based cognitive training with aerobic exercise, compared to the same systematic cognitive training alone. Treatment occurs for 6 months after randomization, with a followup assessment at 12 months. The investigators hypothesize that combining neuroplasticity-based computerized cognitive training and neurotrophin-enhancing physical exercise will produce neurotrophin increases and cognitive and functional improvements, even relative to cognitive training alone. The investigators target the period shortly after a first episode of schizophrenia to maximize the generalization of cognitive improvement to functional outcome, before chronic disability is established.

Primary Outcome

The Overall Composite score from the MCCB is a summary of cognitive performance across seven domains.

Interventions

  • BEHAVIORAL Aerobic Exercise
  • BEHAVIORAL Cognitive Training
  • BEHAVIORAL Case management and supportive psychotherapy
  • BEHAVIORAL Individual Placement and Support

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2016-10-13
Est. Completion 2023-06-30
Phase NA

What the finished NCT02823041 record still lists

NCT02823041 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower).

The record links to 0 conditions, and to 4 interventions - of which Aerobic Exercise is the first listed.

NCT02823041 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02823041 about?

NCT02823041 is a clinical study titled "Enhancing Cognitive Training Through Exercise Following a First Schizophrenia Episode". This is a confirmatory randomized controlled trial of the efficacy of a novel intervention combining neuroplasticity-based cognitive training with aerobic exercise, compared to the same systematic cognitive training alone. Treatment occurs for 6 months after randomization, with a followup assessment...

What is the current status of trial NCT02823041?

This trial is currently completed. It is a NA study. The enrollment target is 100 participants. The study started on 2016-10-13. Estimated completion is 2023-06-30.

What interventions are being tested in trial NCT02823041?

The interventions under investigation include: Aerobic Exercise (BEHAVIORAL), Cognitive Training (BEHAVIORAL), Case management and supportive psychotherapy (BEHAVIORAL), Individual Placement and Support (BEHAVIORAL).

Who is sponsoring clinical trial NCT02823041?

This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02823041's enrollment target sits among peer trials

100 840th of 2000 higher than 1,081 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02823041, the US trial registry maintained by the National Library of Medicine. NCT02823041 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.