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NCT02818751 · ClinicalTrials.gov registry record · NA

Neurofunctional Predictors of Escitalopram Treatment Response in Adolescents With Anxiety

A NA study, sponsored by University of Cincinnati.

Completed
Registry status
NA
Development phase
84
Enrollment target

NCT02818751: Completed NA study, sponsored by University of Cincinnati.

NCT02818751 is a NA study that has completed, run by University of Cincinnati. The registered enrollment target is 84 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02818751, a NA study, has completed, sponsored by University of Cincinnati.

COMPLETED
Registry status
NA
Development phase
84 participants
Enrollment target

Study Summary

Neurofunctional Predictors of Escitalopram Treatment Response in Adolescents with Anxiety. To determine the effects of escitalopram on functional activation patterns during a Continuous Performance Task with Emotional and Neutral Distracters, the CPT-END. To examine baseline functional activity and functional connectivity profiles in the ventrolateral prefrontal cortex as markers of subsequent treatment response to escitalopram in adolescents with generalized anxiety disorder (GAD). To use proton magnetic resonance spectroscopy (1H MRS) to examine glutamatergic and γ-aminobutyric acid (GABA)-related abnormalities in the anterior cingulate in adolescents with GAD as compared to healthy adolescents.

Primary Outcome

To determine if escitalopram treatment (over a 2 week period) increases functional brain activation during the processing of emotional images while performing a continuous processing task with emotional and neutral distracters (CPT-END) (also over a 2 week period).

Interventions

  • OTHER Placebo
  • DRUG Escitalopram

Trial Details

FieldValue
Enrollment Target 84 participants
Start Date 2015-05
Est. Completion 2020-05
Phase NA
University of Cincinnati

245 total trials

What the finished NCT02818751 record still lists

NCT02818751 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 84 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT02818751 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02818751 about?

NCT02818751 is a clinical study titled "Neurofunctional Predictors of Escitalopram Treatment Response in Adolescents With Anxiety". Neurofunctional Predictors of Escitalopram Treatment Response in Adolescents with Anxiety. To determine the effects of escitalopram on functional activation patterns during a Continuous Performance Task with Emotional and Neutral Distracters, the CPT-END. To examine baseline functional activity and ...

What is the current status of trial NCT02818751?

This trial is currently completed. It is a NA study. The enrollment target is 84 participants. The study started on 2015-05. Estimated completion is 2020-05.

What interventions are being tested in trial NCT02818751?

The interventions under investigation include: Placebo (OTHER), Escitalopram (DRUG).

Who is sponsoring clinical trial NCT02818751?

This trial is sponsored by University of Cincinnati, which has 245 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02818751's enrollment target sits among peer trials

84 983rd of 2000 higher than 1,011 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02818751, the US trial registry maintained by the National Library of Medicine. NCT02818751 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.