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NCT02807116 · ClinicalTrials.gov registry record · Phase 1

Drug-Interaction Study to Evaluate the Effect of Rifampin, a Potent CYP3A4 Inducer, on the Systemic Exposure of Pacritinib in Healthy Subjects

A Phase 1 study of Healthy Subjects, sponsored by CTI BioPharma.

Completed
Registry status
Phase 1
Development phase
18
Enrollment target
1
Study location

NCT02807116 is a Phase 1 study of Healthy Subjects that has completed, run by CTI BioPharma. The registered enrollment target is 18 participants, below the 128-participant average among 69 other Healthy Subjects trials with a reported enrollment target (86% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT02807116, a Phase 1 study of Healthy Subjects, has completed, sponsored by CTI BioPharma.

COMPLETED
Registry status
Phase 1
Development phase
18 participants
Enrollment target
1
Study location

Study Summary

The primary objective is to evaluate the effect of rifampin, a potent cytochrome P450 3A4 inducer, at steady-state on the systemic exposure of a single dose of pacritinib in healthy subjects.

Conditions Studied

Interventions

  • DRUG Pacritinib
  • DRUG Rifampin
  • DRUG Pacritinib and Rifampin

Study Locations (1)

Florida

  • Covance Clinical Research Unit - Daytona Beach

Trial Details

FieldValue
Enrollment Target 18 participants
Start Date 2015-01
Est. Completion 2015-02
Phase Phase 1

Sponsor

CTI BioPharma

28 total trials

What the Registry Record Tells You About NCT02807116

The ClinicalTrials.gov registry entry for NCT02807116 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 18 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 128-participant average among 69 other Healthy Subjects trials with a reported enrollment target (86% lower). The listed sponsor is CTI BioPharma, which has 28 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Healthy Subjects appearing as the primary indexed condition, and to 3 interventions - of which Pacritinib is the first listed.

NCT02807116 reports 1 study location spanning 1 distinct geographic area - top geographies include Florida.

Frequently Asked Questions

What is clinical trial NCT02807116 about?

NCT02807116 is a clinical study titled "Drug-Interaction Study to Evaluate the Effect of Rifampin, a Potent CYP3A4 Inducer, on the Systemic Exposure of Pacritinib in Healthy Subjects". The primary objective is to evaluate the effect of rifampin, a potent cytochrome P450 3A4 inducer, at steady-state on the systemic exposure of a single dose of pacritinib in healthy subjects.

What is the current status of trial NCT02807116?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 18 participants. The study started on 2015-01. Estimated completion is 2015-02.

What conditions does trial NCT02807116 study?

This clinical trial studies the following conditions: Healthy Subjects.

What interventions are being tested in trial NCT02807116?

The interventions under investigation include: Pacritinib (DRUG), Rifampin (DRUG), Pacritinib and Rifampin (DRUG).

Who is sponsoring clinical trial NCT02807116?

This trial is sponsored by CTI BioPharma, which has 28 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02807116 being conducted?

This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.