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NCT02798211 · ClinicalTrials.gov registry record · Phase 4

Study to Evaluate the Safety and Efficacy of Secukinumab 300 mg and 150 mg in Adult Patients With Active Psoriatic Arthritis (PsA) After 16 Weeks of Treatment Compared to Placebo

A Phase 4 study, sponsored by Novartis Pharmaceuticals.

Completed
Registry status
Phase 4
Development phase
258
Enrollment target

NCT02798211: Completed Phase 4 study, sponsored by Novartis Pharmaceuticals.

NCT02798211 is a Phase 4 study that has completed, run by Novartis Pharmaceuticals. The registered enrollment target is 258 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (50% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02798211, a Phase 4 study, has completed, sponsored by Novartis Pharmaceuticals.

COMPLETED
Registry status
Phase 4
Development phase
258 participants
Enrollment target

Study Summary

To demonstrate that the efficacy of secukinumab 300 mg at Week 16 was superior to placebo in adult patients with active PsA based on the proportion of patients achieving an American College of Rheumatology 20 (ACR20) response.

Primary Outcome

A patient was considered as improved according to the ACR20 criteria if she/he had at least 20% improvement in two of the following measures:Tender joint count, Swollen joint count and at least 3 of the following 5 measures: Patient's assessment of pain, Patient's global assessment disease activity, Physician's global assessment of disease activity, Health Assessment Questionnaire (HAQ©) score,Acute phase reactant (hsCRP or ESR). Odds ratio, 95% confidence interval for odds ratio, and p-value a

Interventions

  • OTHER Placebo
  • DRUG Secukinumab 300 mg
  • DRUG Secukinumab 150 mg

Trial Details

FieldValue
Enrollment Target 258 participants
Start Date 2016-06-27
Est. Completion 2018-12-05
Phase Phase 4
Novartis Pharmaceuticals

1,375 total trials

What the finished NCT02798211 record still lists

NCT02798211 is an interventional study that assigns participants to a tested intervention. The registered 258 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (50% lower).

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT02798211 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02798211 about?

NCT02798211 is a clinical study titled "Study to Evaluate the Safety and Efficacy of Secukinumab 300 mg and 150 mg in Adult Patients With Active Psoriatic Arthritis (PsA) After 16 Weeks of Treatment Compared to Placebo". To demonstrate that the efficacy of secukinumab 300 mg at Week 16 was superior to placebo in adult patients with active PsA based on the proportion of patients achieving an American College of Rheumatology 20 (ACR20) response.

What is the current status of trial NCT02798211?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 258 participants. The study started on 2016-06-27. Estimated completion is 2018-12-05.

What interventions are being tested in trial NCT02798211?

The interventions under investigation include: Placebo (OTHER), Secukinumab 300 mg (DRUG), Secukinumab 150 mg (DRUG).

Who is sponsoring clinical trial NCT02798211?

This trial is sponsored by Novartis Pharmaceuticals, which has 1,375 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02798211's enrollment target sits among peer trials

258 332nd of 2000 higher than 1,669 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02798211, the US trial registry maintained by the National Library of Medicine. NCT02798211 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.