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NCT02795455 · ClinicalTrials.gov registry record · NA

Reward Systems and Food Avoidance in Eating Disorders

A NA study of Anorexia Nervosa and Low Weight Eating Disorders, sponsored by Icahn School of Medicine at Mount Sinai.

Completed
Registry status
NA
Development phase
90
Enrollment target
1
Study location

NCT02795455: Completed NA study of Anorexia Nervosa and Low Weight Eating Disorders, sponsored by Icahn School of Medicine at Mount Sinai.

NCT02795455 is a NA study of Anorexia Nervosa and Low Weight Eating Disorders that has completed, run by Icahn School of Medicine at Mount Sinai. The registered enrollment target is 90 participants, below the 948-participant average among 43 other Anorexia Nervosa trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02795455, a NA study of Anorexia Nervosa and Low Weight Eating Disorders, has completed, sponsored by Icahn School of Medicine at Mount Sinai.

COMPLETED
Registry status
NA
Development phase
90 participants
Enrollment target
1
Study location

Study Summary

The researchers plan to explore brain networks involved in emotion processing and learning using a brain scan and test meals. One core feature of Anorexia Nervosa (AN) is eating a small number of high-calorie or high-fat foods. By studying why individuals with AN are disgusted by food or other eating situations, the researchers will be able to understand more about the neurobiological pathways that lead to restricting food intake and food avoidance. This study also aims to find whether one of two short-term interventions (Interoceptive Exposure (IE); Family-Based Therapy (FBT)) affects connections in the brain and if the treatments affect food avoidance. IE is an intervention that helps reduce anxiety about eating. FBT is an intervention that motivates patients to eat through working with family to increase the value of eating and decrease the value of avoiding foods.

Primary Outcome

Change in the emotional responses from facial muscle movements to food pictures and non-food pictures as measured with the fMRI-EMG.

Interventions

  • BEHAVIORAL Interoceptive Exposure (IE)
  • BEHAVIORAL Family Based Therapy-Weight Gain Control (FBT-WG)
  • DIETARY_SUPPLEMENT meal replacement shake

Study Locations (1)

New York

  • Icahn School of Medicine at Mount Sinai - New York

Trial Details

FieldValue
Enrollment Target 90 participants
Start Date 2016-11
Est. Completion 2021-07-29
Phase NA

What the finished NCT02795455 record still lists

NCT02795455 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 90 participants, a relatively small participant target, below the 948-participant average among 43 other Anorexia Nervosa trials with a reported enrollment target (91% lower).

The record links to 2 conditions, with Anorexia Nervosa appearing as the primary indexed condition, and to 3 interventions - of which Interoceptive Exposure (IE) is the first listed.

NCT02795455 reports a single indexed study location in New York.

Frequently Asked Questions

What is clinical trial NCT02795455 about?

NCT02795455 is a clinical study titled "Reward Systems and Food Avoidance in Eating Disorders". The researchers plan to explore brain networks involved in emotion processing and learning using a brain scan and test meals. One core feature of Anorexia Nervosa (AN) is eating a small number of high-calorie or high-fat foods. By studying why individuals with AN are disgusted by food or other eatin...

What is the current status of trial NCT02795455?

This trial is currently completed. It is a NA study. The enrollment target is 90 participants. The study started on 2016-11. Estimated completion is 2021-07-29.

What conditions does trial NCT02795455 study?

This clinical trial studies the following conditions: Anorexia Nervosa, Low Weight Eating Disorders.

What interventions are being tested in trial NCT02795455?

The interventions under investigation include: Interoceptive Exposure (IE) (BEHAVIORAL), Family Based Therapy-Weight Gain Control (FBT-WG) (BEHAVIORAL), meal replacement shake (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT02795455?

This trial is sponsored by Icahn School of Medicine at Mount Sinai, which has 708 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02795455 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Anorexia Nervosa

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT02795455's enrollment target sits among peer trials

90 11th of 43 higher than 31 of 43 other Anorexia Nervosa trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Anorexia Nervosa trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02795455, the US trial registry maintained by the National Library of Medicine. NCT02795455 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.