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NCT02788656 · ClinicalTrials.gov registry record · Phase 4
Pulmonary Artery Pressure Reduction With ENTresto (Sacubitril/Valsartan)
A Phase 4 study, sponsored by Brigham and Women's Hospital.
- Terminated
- Registry status
- Phase 4
- Development phase
- 4
- Enrollment target
NCT02788656: Clinical Trial Phase 4 study, sponsored by Brigham and Women's Hospital.
NCT02788656 is a Phase 4 study that was terminated before completion, run by Brigham and Women's Hospital. The registered enrollment target is 4 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02788656, a Phase 4 study, was terminated before completion, sponsored by Brigham and Women's Hospital.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 4 participants
- Enrollment target
Study Summary
This pilot study will assess the impact of sacubitril/valsartan (trade name Entresto) on the elevated pulmonary artery pressures in patients with heart failure with reduced ejection fraction, measured using a previously implanted hemodynamic monitoring device (CardioMEMS).
Primary Outcome
Change in mean PAP in group A versus group B
Interventions
- DRUG sacubitril/valsartan
- DEVICE Implantable Hemodynamic Monitor
- DRUG Angiotensin-Converting Enzyme Inhibitor
- DRUG Angiotensin II Type 1 Receptor Blocker
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2016-09 |
| Est. Completion | 2018-11-09 |
| Phase | Phase 4 |
Why NCT02788656 stopped before completion
NCT02788656 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 4 interventions - of which sacubitril/valsartan is the first listed.
NCT02788656 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02788656 about?
NCT02788656 is a clinical study titled "Pulmonary Artery Pressure Reduction With ENTresto (Sacubitril/Valsartan)". This pilot study will assess the impact of sacubitril/valsartan (trade name Entresto) on the elevated pulmonary artery pressures in patients with heart failure with reduced ejection fraction, measured using a previously implanted hemodynamic monitoring device (CardioMEMS).
What is the current status of trial NCT02788656?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 4 participants. The study started on 2016-09. Estimated completion is 2018-11-09.
What interventions are being tested in trial NCT02788656?
The interventions under investigation include: sacubitril/valsartan (DRUG), Implantable Hemodynamic Monitor (DEVICE), Angiotensin-Converting Enzyme Inhibitor (DRUG), Angiotensin II Type 1 Receptor Blocker (DRUG).
Who is sponsoring clinical trial NCT02788656?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02788656's enrollment target sits among peer trials
4 1994th of 2000 higher than 6 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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