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NCT02782715 · ClinicalTrials.gov registry record · Phase 1

Microwave Ablation With MRI-Guided SBRT Boost in Renal Cell Carcinoma

A Phase 1 study, sponsored by University of Wisconsin, Madison.

Terminated
Registry status
Phase 1
Development phase
3
Enrollment target

NCT02782715: Clinical Trial Phase 1 study, sponsored by University of Wisconsin, Madison.

NCT02782715 is a Phase 1 study that was terminated before completion, run by University of Wisconsin, Madison. The registered enrollment target is 3 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02782715, a Phase 1 study, was terminated before completion, sponsored by University of Wisconsin, Madison.

TERMINATED
Registry status
Phase 1
Development phase
3 participants
Enrollment target

Study Summary

The specific aims of this study are: 1. To determine the safety and feasibility of treating patients with a combination of MRI guided stereotactic body radiation therapy and microwave ablation. 2. To assess short and long-term toxicity rates of patients treated with a combined modality approach. 3. To assess local control, survival, and pathologic response to treatment

Primary Outcome

Dose-limiting toxicity (DLT) will be defined as grade 4 or higher non-hematologic toxicity attributable to treatment. This will exclude toxicities not caused by treatment, such as pain due to tumor progression. Toxicities will be defined per NCI CTCAE v5.0.

Interventions

  • RADIATION Stereotactic Body Radiation Therapy (SBRT)
  • PROCEDURE Microwave Ablation (MWA)

Trial Details

FieldValue
Enrollment Target 3 participants
Start Date 2018-06-28
Est. Completion 2023-01-10
Phase Phase 1
University of Wisconsin, Madison

1,039 total trials

Why NCT02782715 stopped before completion

NCT02782715 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (95% lower).

The record links to 0 conditions, and to 2 interventions - of which Stereotactic Body Radiation Therapy (SBRT) is the first listed.

NCT02782715 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02782715 about?

NCT02782715 is a clinical study titled "Microwave Ablation With MRI-Guided SBRT Boost in Renal Cell Carcinoma". The specific aims of this study are: 1. To determine the safety and feasibility of treating patients with a combination of MRI guided stereotactic body radiation therapy and microwave ablation. 2. To assess short and long-term toxicity rates of patients treated with a combined modality approach. 3....

What is the current status of trial NCT02782715?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 3 participants. The study started on 2018-06-28. Estimated completion is 2023-01-10.

What interventions are being tested in trial NCT02782715?

The interventions under investigation include: Stereotactic Body Radiation Therapy (SBRT) (RADIATION), Microwave Ablation (MWA) (PROCEDURE).

Who is sponsoring clinical trial NCT02782715?

This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02782715's enrollment target sits among peer trials

3 1999th of 2000 higher than 1 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02782715, the US trial registry maintained by the National Library of Medicine. NCT02782715 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.