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NCT02780479 · ClinicalTrials.gov registry record · Phase 4
Steroids in Children Hospitalized With Asthma
A Phase 4 study, sponsored by University of Florida.
- Terminated
- Registry status
- Phase 4
- Development phase
- 6
- Enrollment target
NCT02780479 is a Phase 4 study that was terminated before completion, run by University of Florida. The registered enrollment target is 6 participants.
The verdict
NCT02780479, a Phase 4 study, was terminated before completion, sponsored by University of Florida.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 6 participants
- Enrollment target
Study Summary
Asthma is the most common chronic disease of children. A short (3-5 day) course of a short-acting steroid such as Prednisone or Prednisolone has long been the standard of care for asthma exacerbation. Dexamethasone efficacy in asthma exacerbation has been studied in the outpatient setting and was found to be as effective as Prednisone. Dexamethasone has the advantage of shorter course, more compliance, and more tolerable. This has led many emergency departments to provide a 1-2 dose course of Dexamethasone on discharge. Thus, many inpatients have received a first dose of Dexamethasone prior to reaching the inpatient unit, leading to confusion about the best plan for these patients. Many hospitalist pediatricians continue to give a 5-day total course with Prednisone, but some patients have begun to receive a second dose of Dexamethasone 24 hours after the first dose. To our knowledge, no studies have been done to compare the efficacy of these two protocols in pediatric patients requiring hospitalization. The hypothesis is that a second dose of Dexamethasone is as effective as four additional days of Prednisone in hospitalized children with asthma exacerbation. This is an open label, randomized control study comparing these treatments in children age 2-18 hospitalized with asthma exacerbation who have received a first dose of Dexamethasone.
Interventions
- DRUG Dexamethasone
- DRUG Prednisone
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 6 participants |
| Start Date | 2017-03-20 |
| Est. Completion | 2017-08-29 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02780479
The ClinicalTrials.gov registry entry for NCT02780479 describes a study currently listed as terminated, categorized as Phase 4. The registered enrollment target is 6 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Florida, which has 1,106 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Dexamethasone is the first listed.
NCT02780479 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02780479 about?
NCT02780479 is a clinical study titled "Steroids in Children Hospitalized With Asthma". Asthma is the most common chronic disease of children. A short (3-5 day) course of a short-acting steroid such as Prednisone or Prednisolone has long been the standard of care for asthma exacerbation. Dexamethasone efficacy in asthma exacerbation has been studied in the outpatient setting and was fo...
What is the current status of trial NCT02780479?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 6 participants. The study started on 2017-03-20. Estimated completion is 2017-08-29.
What interventions are being tested in trial NCT02780479?
The interventions under investigation include: Dexamethasone (DRUG), Prednisone (DRUG).
Who is sponsoring clinical trial NCT02780479?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
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